ecoza
Ecoza (Econazole Nitrate) is an azole antifungal used to treat Cutaneous Candidiasis, Tinea Pedis, Tinea Versicolor.
Econazole Nitrate · by Resilia Pharms
Available as a generic: Econazole Nitrate
Key facts
- Active ingredient
- Econazole Nitrate
- Drug class
- Azole Antifungal
- Form
- Spray/Inhaler, Topical
- Strength
- Econazole Nitrate 1%
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- May treat
- cutaneous candidiasis, tinea pedis, tinea versicolor
- Manufacturer
- Resilia Pharms
- What the pharmacy pays
- ~$0.36 per gm — not your price
- FDA application
- NDA205175
What is Ecoza?
From the FDA label:Ecoza (econazole nitrate) topical foam, 1% contains the azole antifungal agent, econazole nitrate in an oil-in-water emulsion base consisting of the following inactive ingredients: dimethicone, glycerin, polysorbate 20, povidone, propylene glycol, stearic acid, trolamine, purified water and butane as a propellant. Each gram of Ecoza topical foam, 1% contains 10 mg of econazole nitrate, USP, in a white to off-white foam. Ecoza topical foam, 1% is alcohol (ethanol)-free and for topical use only. Chemically, econazole nitrate is 1-[2-{(4-chloro-phenyl)methoxy}-2-(2,4-dichlorophenyl) ethyl]-1H-imidazole mononitrate. Econazole nitrate has the molecular formula C 18 H 15 Cl 3 N 2 O. HNO 3 and a molecular weight of 444.70. Its molecular structure is as follows: Chemical Structure
How to use
Ecoza is sold in more than one form (Spray/Inhaler and Topical), and each is dosed differently. The instructions below come from the FDA label for application NDA205175 — follow the label that came with the product you were actually prescribed.
Ecoza topical foam, 1% is for topical use only. Ecoza topical foam, 1% is not for oral, ophthalmic, or intravaginal use. Ecoza topical foam, 1% should be applied to cover affected areas once daily for 4 weeks. For topical use only; not for oral, ophthalmic, or intravaginal use. ( 2 ) Apply once daily for 4 weeks. ( 2 )
Side effects
During clinical trials with Ecoza topical foam, the most common adverse reactions were application site reactions which occurred in less than 1% of subjects in both the Ecoza and vehicle arms. ( 6.1 ) To report SUSPECTED ADVERSE REACTIONS, contact Resilia Pharmaceuticals at 1-888-998-0770 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. In two double-blind, vehicle-controlled clinical trials, 495 subjects were exposed to Ecoza topical foam or vehicle (246 subjects were exposed to Ecoza topical foam, 1% and 249 were exposed to vehicle). Subjects with interdigital tinea pedis applied foam or vehicle once daily for approximately 28 days. During clinical trials with Ecoza topical foam, the most common adverse reactions were application site reactions which occurred in less than 1% of subjects in both the Ecoza and vehicle arms.
Warnings
Important safety information
Contents are flammable. Instruct the patient to avoid heat, flame, and/or smoking during and immediately following application. ( 5.1 ) 5.1 Flammability Ecoza topical foam is flammable. Avoid heat, flame, and smoking during and immediately following application. Contents under pressure. Do not puncture and/or incinerate the containers. Do not expose containers to heat and/or store at temperatures above 120°F (49°C) even when empty. Do not store in direct sunlight.
Who should not take Ecoza
None. None. ( 4 )
Interactions
7.1 Warfarin Concomitant administration of econazole and warfarin has resulted in enhancement of anticoagulant effect. Most cases reported product application with use under occlusion, genital application, or application to a large body surface area which may increase the systemic absorption of econazole nitrate. Monitoring of International Normalized Ratio (INR) and/or prothrombin time may be indicated especially for patients who apply econazole to large body surface areas, in the genital area, or under occlusion.
Drug class
How this class works, per Antifungal Ergosterol Synthesis Inhibitors — StatPearls, NCBI Bookshelf (NIH).
May treat (source: NIH RxClass)
See how Ecoza ranks — best-rated azole antifungal for:
Dosage forms
Spray/Inhaler and Topical
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Ecoza treat?
- Ecoza (Econazole Nitrate) may be used to treat cutaneous candidiasis, tinea pedis, tinea versicolor, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How does Ecoza work?
- Ecoza is a azole antifungal. Azole antifungals block a fungal enzyme (lanosterol 14-alpha-demethylase) that the fungus needs to make ergosterol, a key building block of its cell membrane. Without enough ergosterol the membrane becomes leaky and unstable, which stops the fungus from growing and can cause it to break apart and die.
- How much does Ecoza cost?
- Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.36 per gm, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Ketoconazole — about $0.27 on the same basis.
- Is there a coupon or discount for Ecoza?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Ecoza. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Ecoza?
- Ecoza is marketed by Resilia Pharms. You can see Resilia Pharms's full profile, rating, and other products on pharmaranks.
- Is Ecoza a brand-name or generic drug?
- Ecoza is a brand-name product with the active ingredient Econazole Nitrate. Lower-cost generic equivalents containing Econazole Nitrate are available — ask your pharmacist.
- Is Ecoza available over the counter?
- No. Ecoza is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Ecoza come in?
- Ecoza is currently marketed as spray/inhaler and topical, per the FDA's National Drug Code Directory.
- What class of drug is Ecoza?
- Ecoza is classified as azole antifungal, per the FDA's Established Pharmacologic Class.
- Is Ecoza FDA-registered?
- Ecoza is on record with the U.S. FDA under application number NDA205175. You can verify this on its official FDA label.
- Is Ecoza safe?
- There's no single safe-or-not verdict, and we don't yet have a composite recall-safety score for Ecoza. Review its FDA-label side effects and warnings below, and always consult a licensed professional.
- What are the side effects of Ecoza?
- Ecoza's side effects are taken directly from its FDA label. From the label: During clinical trials with Ecoza topical foam, the most common adverse reactions were application site reactions which occurred in less than 1% of subjects in both the Ecoza and vehicle arms. ( 6.1 ) To report SUSPECTED ADVERSE REACTIONS,… Both common and serious reactions are documented in full on this page. This is general reference from the FDA, not medical advice — always consult a professional.
Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
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