Which pills you can crush or split
Quoted from each drug’s own FDA label, per product — because the answer belongs to the form, not the drug name. An extended-release tablet releases a whole day’s dose at once when it is crushed; the immediate-release version of the same drug often carries no restriction at all.
Drugs whose labels carry an instruction (177)
Can you crush Acetaminophen?
Swallow whole — the label says not to crush or chew it · Acetaminophen
“Adults: take 2 tablets every 8 hours with water swallow whole; do not crush, chew, split or dissolve do not take more than 6 tablets in 24 hours do not use for more than 10 days unless directed by a doctor.” label ↗
50 labels read
Can you crush Albendazole?
The label allows it, in the terms quoted · ALBENZA
“ALBENZA tablets may be crushed or chewed and swallowed with a drink of water.” label ↗
10 labels read
Can you crush Alfuzosin?
Swallow whole — the label says not to crush or chew it · Alfuzosin Hydrochloride
“The tablets should not be chewed or crushed.” label ↗
17 labels read
Can you crush Alprazolam?
Swallow whole — the label says not to crush or chew it · Alprazolam
“Swallow tablets whole; do not divide, crush, or chew.” label ↗
50 labels read
Can you crush Amantadine?
Swallow whole — the label says not to crush or chew it · GOCOVRI
“Do not crush, chew, or divide.” label ↗
The label allows it, in the terms quoted · Amantadine HCL
“The daily dosage may be split into one tablet of 100 mg twice a day.” label ↗
50 labels read
Can you crush Ambrisentan?
Swallow whole — the label says not to crush or chew it · Ambrisentan
“Do not split, crush, or chew tablets.” label ↗
14 labels read
Can you crush Apixaban?
Swallow whole — the label says not to crush or chew it · ELIQUIS
“For patients who are unable to swallow whole tablets, 5 mg and 2.” label ↗
It depends on what you mean — read the sentence · apixaban
“D5W), or apple juice, or mixed with applesauce and promptly administered orally [see Clinical Pharmacology.” label ↗
The label allows it, in the terms quoted · ELIQUIS
“Alternatively, ELIQUIS tablets may be crushed and suspended in 60 mL of water or D5W and promptly delivered through a nasogastric tube [see Clinical Pharmacology.” label ↗
11 labels read
Can you crush Asenapine?
Swallow whole — the label says not to crush or chew it · Asenapine
“Do not cut or tear the tablet pack.” label ↗
7 labels read
Can you crush Azacitidine?
Swallow whole — the label says not to crush or chew it · ONUREG
“Do not cut, crush, or chew the tablets.” label ↗
27 labels read
Can you crush Balsalazide Disodium?
Swallow whole — the label says not to crush or chew it · Balsalazide Disodium
“Do not cut, break, crush or chew.” label ↗
The label allows it, in the terms quoted · Balsalazide Disodium
“The contents may be chewed, if necessary.” label ↗
9 labels read
Can you crush Barium?
Swallow whole — the label says not to crush or chew it · E-Z-Disk
“Do not cut, crush, or chew the tablet.” label ↗
50 labels read
Can you crush Benzonatate?
Swallow whole — the label says not to crush or chew it · Benzonatate
“BENZONATATE should be swallowed whole.” label ↗
50 labels read
Can you crush Bosentan?
Swallow whole — the label says not to crush or chew it · Bosentan
“Decreases in sperm count, Fluid retention Administration Considerations Advise patients that bosentan tablets for oral suspension dispersible tablets should not be split into quarters.” label ↗
8 labels read
Can you crush Bosutinib?
Swallow whole — the label says not to crush or chew it · BOSULIF
“Capsules may be swallowed whole.” label ↗
5 labels read
Can you crush Brivaracetam?
Swallow whole — the label says not to crush or chew it · Briviact
“BRIVIACT tablets should not be chewed or crushed.” label ↗
20 labels read
Can you crush Budesonide?
Swallow whole — the label says not to crush or chew it · Budesonide
“Do not chew or crush the granules.” label ↗
50 labels read
Can you crush Buprenorphine?
Swallow whole — the label says not to crush or chew it · Buprenorphine
“Do not cut, chew, or swallow buprenorphine sublingual tablet.” label ↗
50 labels read
Can you crush Bupropion?
Swallow whole — the label says not to crush or chew it · Bupropion Hydrochloride SR
“Do not chew, divide, or crush tablets; they are designed to slowly release drug in the body.” label ↗
50 labels read
Can you crush Caffeine?
Swallow whole — the label says not to crush or chew it · Uplift Chewable
“Do not swallow whole Warnings For occasional use only.” label ↗
50 labels read
Can you crush Capecitabine?
Swallow whole — the label says not to crush or chew it · Capecitabine
“Do not crush or cut capecitabine tablets.” label ↗
21 labels read
Can you crush Carbamazepine?
Swallow whole — the label says not to crush or chew it · Carbamazepine
“Tegretol-XR tablets must be swallowed whole and never crushed or chewed.” label ↗
50 labels read
Can you crush Carglumic Acid?
Swallow whole — the label says not to crush or chew it · Carbaglu
“Do not swallow whole or crush.” label ↗
4 labels read
Can you crush Carvedilol?
Swallow whole — the label says not to crush or chew it · Carvedilol Phosphate
“Do not crush or chew capsules.” label ↗
50 labels read
Can you crush Cefaclor?
The label allows it, in the terms quoted · Cefaclor
“Treatment Option —For the treatment of otitis media and pharyngitis, the total daily dosage may be divided and administered every 12 hours.” label ↗
4 labels read
Can you crush Cefixime?
The label allows it, in the terms quoted · Cefixime
“This may be given as a 400 mg tablet daily or the 400 mg tablet may be split and given as one half tablet every 12 hours.” label ↗
8 labels read
Can you crush Cephalexin?
The label allows it, in the terms quoted · CEPHALEXIN
“For streptococcal pharyngitis in patients over 1 year of age and for skin and skin structure infections, the total daily dose may be divided and administered every 12 hours.” label ↗
50 labels read
Can you crush Ciprofloxacin?
Swallow whole — the label says not to crush or chew it · Ciprofloxacin
“Not to chew the microcapsules, but to swallow them whole.” label ↗
The label allows it, in the terms quoted · Ciprofloxacin
“Advise patients that ciprofloxacin tablets (250 mg and 500 mg) are scored and can be split into one-half at the scored line to provide a 125 mg or 250 mg strength, respectively.” label ↗
50 labels read
Can you crush Cladribine?
Swallow whole — the label says not to crush or chew it · Mavenclad
“MAVENCLAD tablets are taken orally, with water, and swallowed whole without chewing.” label ↗
8 labels read
Can you crush Clarithromycin?
Swallow whole — the label says not to crush or chew it · Clarithromycin
“Swallow clarithromycin extended-release tablets whole; do not chew, break or crush clarithromycin extended-release tablets.” label ↗
44 labels read
Can you crush Clindamycin?
Swallow whole — the label says not to crush or chew it · Clindamycin Phosphate
“Do not break through (puncture) the clindamycin phosphate foam can.” label ↗
50 labels read
Can you crush Clobazam?
Swallow whole — the label says not to crush or chew it · SYMPAZAN
“Do not chew, spit, or talk while SYMPAZAN dissolves.” label ↗
22 labels read
Can you crush Clobetasol?
Swallow whole — the label says not to crush or chew it · Tovet (emollient formulation)
“Do not break through (puncture) Tovet Foam can.” label ↗
50 labels read
Can you crush Clonidine?
Swallow whole — the label says not to crush or chew it · Clonidine Hydrochloride
“Do not crush, chew or break tablet before swallowing.” label ↗
50 labels read
Can you crush Clozapine?
The label allows it, in the terms quoted · Clozapine
“The tablets can be allowed to disintegrate, or they may be chewed.” label ↗
15 labels read
Can you crush Colestipol?
Swallow whole — the label says not to crush or chew it · Colestipol hydrochloride
“Do not cut, crush or chew the tablets.” label ↗
12 labels read
Can you crush Copper?
Swallow whole — the label says not to crush or chew it · Miudella
“Completely remove the white release thread from the inserter until you see the free end of the thread Do not cut the white release thread.” label ↗
50 labels read
Can you crush Cyclophosphamide?
Swallow whole — the label says not to crush or chew it · Cyclophosphamide
“The tablets should not be chewed or crushed.” label ↗
33 labels read
Can you crush Cysteamine?
Swallow whole — the label says not to crush or chew it · PROCYSBI
“Do not crush or chew oral granules.” label ↗
4 labels read
Can you crush Dabigatran Etexilate?
Swallow whole — the label says not to crush or chew it · Pradaxa
“PRADAXA Capsules should be swallowed whole.” label ↗
21 labels read
Can you crush Dalfampridine?
Swallow whole — the label says not to crush or chew it · Dalfampridine
“Administer tablets whole; do not divide, crush, chew, or dissolve.” label ↗
12 labels read
Can you crush Darifenacin?
Swallow whole — the label says not to crush or chew it · Darifenacin
“Do not chew, cut or crush darifenacin extended-release tablet.” label ↗
10 labels read
Can you crush Dasatinib?
Swallow whole — the label says not to crush or chew it · Dasatinib
“Do not crush, cut or chew tablets.” label ↗
16 labels read
Can you crush Desvenlafaxine?
Swallow whole — the label says not to crush or chew it · Pristiq Extended-Release
“Take tablets whole; do not divide, crush, chew, or dissolve.” label ↗
46 labels read
Can you crush Dexmethylphenidate?
Swallow whole — the label says not to crush or chew it · Dexmethylphenidate Hydrochloride
“The dose of a single capsule should not be divided.” label ↗
42 labels read
Can you crush Diethylpropion?
Swallow whole — the label says not to crush or chew it · Diethylpropion Hydrochloride ER
“Diethylpropion Hydrochloride Extended Release Tablets, 75 mg: One extended-release 75 mg tablet daily, swallowed whole, in midmorning.” label ↗
23 labels read
Can you crush Diflunisal?
Swallow whole — the label says not to crush or chew it · Diflunisal
“Tablets should be swallowed whole, not crushed or chewed.” label ↗
6 labels read
Can you crush Diltiazem?
Swallow whole — the label says not to crush or chew it · Diltiazem Hydrochloride
“Do not split diltiazem tablets.” label ↗
50 labels read
Can you crush Dimethyl?
Swallow whole — the label says not to crush or chew it · TECFIDERA
“TECFIDERA should be swallowed whole and intact.” label ↗
30 labels read
Can you crush Diphenhydramine?
It depends on what you mean — read the sentence · Nighttime Sleep-Aid
“Warnings Do not use ■ for children under 12 years of age ■ with any other product containing diphenhydramine, even one used on skin.” label ↗
50 labels read
Can you crush Divalproex?
Swallow whole — the label says not to crush or chew it · Depakote
“Depakote should be swallowed whole and should not be crushed or chewed.” label ↗
50 labels read
Can you crush Dolutegravir?
Swallow whole — the label says not to crush or chew it · Tivicay
“Do not chew, cut, or crush the tablets.” label ↗
5 labels read
Can you crush Donepezil?
Swallow whole — the label says not to crush or chew it · DONEPEZIL HYDROCHLORIDE
“Do not split, crush, or chew the tablets.” label ↗
50 labels read
Can you crush Doxazosin?
Swallow whole — the label says not to crush or chew it · Cardura XL
“Do not chew, divide, cut, or crush CARDURA XL tablets before swallowing.” label ↗
50 labels read
Can you crush Doxycycline?
Swallow whole — the label says not to crush or chew it · DOXYCYCLINE HYCLATE
“Do not chew or crush tablets [see Dosage and Administration.” label ↗
50 labels read
Can you crush Drospirenone?
Swallow whole — the label says not to crush or chew it · SLYND
“How to Take SLYND SLYND (white active and green inert tablets) is swallowed whole once a day.” label ↗
32 labels read
Can you crush Duloxetine?
Swallow whole — the label says not to crush or chew it · Duloxetine Delayed-Release
“Swallow whole; do not crush, chew, or open capsule.” label ↗
50 labels read
Can you crush Dutasteride?
Swallow whole — the label says not to crush or chew it · Dutasteride
“Dosing considerations: Swallow whole.” label ↗
27 labels read
Can you crush Efavirenz?
Swallow whole — the label says not to crush or chew it · Efavirenz
“Table 1: Efavirenz Dosing in Pediatric Patients b Tablets must not be crushed.” label ↗
16 labels read
Can you crush Eltrombopag Olamine?
Swallow whole — the label says not to crush or chew it · Eltrombopag
“Do not split, chew, or crush tablets and mix with food or liquids.” label ↗
6 labels read
Can you crush Enalapril?
The label allows it, in the terms quoted · Enalapril maleate oral solution
“The dose may be divided and administered twice daily if the antihypertensive effect diminishes at the end of the dosing interval.” label ↗
50 labels read
Can you crush Erythromycin Ethylsuccinate?
Swallow whole — the label says not to crush or chew it · ERYTHROMYCIN ETHYLSUCCINATE
“To avoid unpleasant taste, the 400 mg tablets should not be chewed.” label ↗
15 labels read
Can you crush Esomeprazole?
Swallow whole — the label says not to crush or chew it · Acid Reducer
“Do not crush or chew capsules.” label ↗
50 labels read
Can you crush Everolimus?
Swallow whole — the label says not to crush or chew it · Everolimus
“Do not break or crush tablets.” label ↗
21 labels read
Can you crush Felodipine?
Swallow whole — the label says not to crush or chew it · Felopdipine
“Felodipine should be swallowed whole and not crushed or chewed.” label ↗
33 labels read
Can you crush Fenofibrate?
Swallow whole — the label says not to crush or chew it · FENOFIBRATE
“Do not crush, dissolve or chew tablets.” label ↗
50 labels read
Can you crush Ferric?
Swallow whole — the label says not to crush or chew it · Auryxia
“Auryxia tablets must not be chewed or crushed because it may cause discoloration of mouth and teeth.” label ↗
41 labels read
Can you crush Fluvastatin?
Swallow whole — the label says not to crush or chew it · Lescol XL
“Do not break, crush or chew LESCOL XL tablets.” label ↗
11 labels read
Can you crush Gabapentin?
Swallow whole — the label says not to crush or chew it · GABAPENTIN
“Do not crush, split, or chew the tablets.” label ↗
50 labels read
Can you crush Glipizide?
Swallow whole — the label says not to crush or chew it · Glipizide
“Do not break, crush, dissolve, chew, or cut the tablet in half.” label ↗
50 labels read
Can you crush Granisetron?
Swallow whole — the label says not to crush or chew it · SANCUSO
“Do not cut the transdermal system.” label ↗
10 labels read
Can you crush Guanfacine?
Swallow whole — the label says not to crush or chew it · Intuniv
“Do not crush, chew, or break INTUNIV.” label ↗
50 labels read
Can you crush Ibandronate?
Swallow whole — the label says not to crush or chew it · IBANDRONATE SODIUM
“Do not chew or suck the tablet because of a potential for oropharyngeal ulceration.” label ↗
10 labels read
Can you crush Icosapent Ethyl?
Swallow whole — the label says not to crush or chew it · Vascepa
“Do not break open, crush, dissolve, or chew VASCEPA.” label ↗
30 labels read
Can you crush Imatinib?
Swallow whole — the label says not to crush or chew it · Imatinib Mesylate
“Do not crush imatinib mesylate tablets.” label ↗
The label allows it, in the terms quoted · Gleevec
“Gleevec treatment can be given as a once daily dose or the daily dose may be split into two–one portion dosed in the morning and one portion in the evening.” label ↗
25 labels read
Can you crush Iodide?
The label allows it, in the terms quoted · Thyrosafe
“Tablets can be crushed and mixed in many liquids.” label ↗
50 labels read
Can you crush Isosorbide Mononitrate?
Swallow whole — the label says not to crush or chew it · Isosorbide Mononitrate
“Do not break the 30 mg tablet.” label ↗
38 labels read
Can you crush Isotretinoin?
Swallow whole — the label says not to crush or chew it · Isotretinoin
“Do not split, crush, chew, or suck on the capsules.” label ↗
21 labels read
Can you crush Itraconazole?
Swallow whole — the label says not to crush or chew it · Tolsura
“TOLSURA capsules must be swallowed whole.” label ↗
15 labels read
Can you crush Ketoconazole?
Swallow whole — the label says not to crush or chew it · Ketodan
“Do not break through (puncture) the Ketodan ® Foam, 2% can.” label ↗
50 labels read
Can you crush Lacosamide?
Swallow whole — the label says not to crush or chew it · Lacosamide
“Do not cut lacosamide tablets.” label ↗
50 labels read
Can you crush Lamotrigine?
Swallow whole — the label says not to crush or chew it · Lamotrigine
“Tablets must be swallowed whole and must not be chewed, crushed, or divided.” label ↗
50 labels read
Can you crush Lansoprazole?
Swallow whole — the label says not to crush or chew it · Lansoprazole
“Do not crush or chew capsules.” label ↗
50 labels read
Can you crush Lenalidomide?
Swallow whole — the label says not to crush or chew it · Revlimid
“REVLIMID should be swallowed whole with water.” label ↗
21 labels read
Can you crush Levetiracetam?
Swallow whole — the label says not to crush or chew it · Keppra
“KEPPRA tablets should be swallowed whole.” label ↗
50 labels read
Can you crush Levothyroxine?
The label allows it, in the terms quoted · Levothyroxine Sodium
“Levothyroxine Sodium Tablets, USP may be administered to infants and children who cannot swallow intact tablets by crushing the tablet and suspending the freshly crushed tablet in a small amount (5-10 mL or 1-2 teaspoons) of water.” label ↗
50 labels read
Can you crush Lisdexamfetamine Dimesylate?
Swallow whole — the label says not to crush or chew it · Lisdexamfetamine Dimesylate
“A single dose should not be divided.” label ↗
29 labels read
Can you crush Lithium?
Swallow whole — the label says not to crush or chew it · Lithium Carbonate
“Lithium carbonate extended-release tablets must be swallowed whole and never chewed or crushed.” label ↗
50 labels read
Can you crush Lomustine?
Swallow whole — the label says not to crush or chew it · Gleostine
“Do not break Gleostine capsules; avoid exposure to broken capsules.” label ↗
4 labels read
Can you crush Lorazepam?
Swallow whole — the label says not to crush or chew it · LOREEV XR
“Do not crush or chew LOREEV XR.” label ↗
50 labels read
Can you crush Lubiprostone?
Swallow whole — the label says not to crush or chew it · Lubiprostone
“Swallow capsules whole and do not break apart or chew.” label ↗
25 labels read
Can you crush Meclizine?
Swallow whole — the label says not to crush or chew it · Meclizine Hydrochloride
“Instructions Meclizine hydrochloride tablets must be swallowed whole.” label ↗
50 labels read
Can you crush Mefloquine?
It depends on what you mean — read the sentence · Mefloquine Hydrochloride
“The tablets may be crushed and suspended in a small amount of water, milk or other beverage for administration to small children and other persons unable to swallow them whole.” label ↗
3 labels read
Can you crush Memantine?
Swallow whole — the label says not to crush or chew it · Memantine Hydrochloride
“The capsules should not be divided, chewed or crushed.” label ↗
50 labels read
Can you crush Mesalamine?
Swallow whole — the label says not to crush or chew it · Mesalamine
“Do not cut or break the suppository.” label ↗
50 labels read
Can you crush Metformin?
Swallow whole — the label says not to crush or chew it · Metformin hydrochloride
“Do not crush, cut, or chew the tablets.” label ↗
50 labels read
Can you crush Methadone?
Swallow whole — the label says not to crush or chew it · METHADOSE DISPERSIBLE
“The tablets should not be chewed or swallowed before dispersing in liquid.” label ↗
35 labels read
Can you crush Methylphenidate?
Swallow whole — the label says not to crush or chew it · RELEXXII
“Do not chew, divide, or crush.” label ↗
50 labels read
Can you crush Metoprolol?
It depends on what you mean — read the sentence · Metoprolol Succinate
“Metoprolol succinate extended-release tablets are scored and can be divided; however, do not crush or chew the whole or half tablet.” label ↗
50 labels read
Can you crush Mifepristone?
Swallow whole — the label says not to crush or chew it · Korlym
“Do not split, crush, or chew tablets.” label ↗
5 labels read
Can you crush Minocycline?
Swallow whole — the label says not to crush or chew it · MINOCYCLINE HYDROCHLORIDE
“The tablets should be swallowed whole.” label ↗
50 labels read
Can you crush Mirabegron?
Swallow whole — the label says not to crush or chew it · MIRABEGRON
“Do not chew, divide, or crush.” label ↗
14 labels read
Can you crush Morphine?
Swallow whole — the label says not to crush or chew it · Morphine sulfate
“Do not crush, chew, or dissolve the tablets [see Dosage and Administration.” label ↗
50 labels read
Can you crush Mycophenolate Mofetil?
Swallow whole — the label says not to crush or chew it · Mycophenolate Mofetil
“Mycophenolate mofetil tablets should not be crushed.” label ↗
47 labels read
Can you crush Nevirapine?
Swallow whole — the label says not to crush or chew it · NEVIRAPINE
“They must not be chewed, crushed, or divided.” label ↗
9 labels read
Can you crush Nicotine?
Swallow whole — the label says not to crush or chew it · Kirkland Signature Nicotine
“Do not chew or swallow lozenge.” label ↗
50 labels read
Can you crush Nicotine Polacrilex?
Swallow whole — the label says not to crush or chew it · Nicotine Polacrilex
“Do not chew or swallow lozenge.” label ↗
50 labels read
Can you crush Nifedipine?
Swallow whole — the label says not to crush or chew it · Nifedipine
“Do not chew, divide or crush tablets.” label ↗
50 labels read
Can you crush Nilotinib?
Swallow whole — the label says not to crush or chew it · DANZITEN
“Do not cut, crush, or chew the tablets.” label ↗
11 labels read
Can you crush Nimodipine?
Swallow whole — the label says not to crush or chew it · nimodipine
“In general, the capsules should be swallowed whole with a little liquid, preferably not less than one hour before or two hours after meals.” label ↗
4 labels read
Can you crush Nintedanib?
Swallow whole — the label says not to crush or chew it · nintedanib
“3) ] and swallowed whole with liquid.” label ↗
11 labels read
Can you crush Nitisinone?
The label allows it, in the terms quoted · NITYR
“For patients who can swallow semi-solid foods, NITYR tablets can be crushed and mixed with applesauce.” label ↗
10 labels read
Can you crush Nitroglycerin?
Swallow whole — the label says not to crush or chew it · Nitroglycerin
“Do not chew, crush, or swallow nitroglycerin sublingual tablets.” label ↗
50 labels read
Can you crush Omega-3-Acid Ethyl Esters?
Swallow whole — the label says not to crush or chew it · Lovaza
“Do not break open, crush, dissolve, or chew LOVAZA.” label ↗
26 labels read
Can you crush Omeprazole?
Swallow whole — the label says not to crush or chew it · omeprazole
“Do not chew or crush capsules.” label ↗
50 labels read
Can you crush Oxcarbazepine?
Swallow whole — the label says not to crush or chew it · Oxcarbazepine
“Do not cut, chew, or crush the tablet.” label ↗
50 labels read
Can you crush Oxybutynin?
Swallow whole — the label says not to crush or chew it · OXYTROL
“Do not divide or cut the patch into pieces.” label ↗
50 labels read
Can you crush Oxybutynin Chloride?
Swallow whole — the label says not to crush or chew it · Oxybutynin Chloride Extended Release
“Patients should be informed that Oxybutynin chloride extended-release tablets should be swallowed whole with the aid of liquids.” label ↗
50 labels read
Can you crush Palbociclib?
Swallow whole — the label says not to crush or chew it · Ibrance
“Do not chew, crush or split IBRANCE tablets before swallowing them.” label ↗
3 labels read
Can you crush Paliperidone?
Swallow whole — the label says not to crush or chew it · INVEGA HAFYERA
“Do not divide dose into multiple injections.” label ↗
29 labels read
Can you crush Pantoprazole?
Swallow whole — the label says not to crush or chew it · Pantoprazole Sodium
“Do not split, crush, or chew pantoprazole sodium delayed-release tablets.” label ↗
50 labels read
Can you crush Pazopanib?
Swallow whole — the label says not to crush or chew it · Pazopanib
“Do not crush tablets due to the potential for increased rate of absorption, which may affect systemic exposure [see Clinical Pharmacology.” label ↗
9 labels read
Can you crush Phenylbutyrate?
Swallow whole — the label says not to crush or chew it · PHEBURANE
“Do not chew PHEBURANE oral pellets directly or mix into liquids.” label ↗
15 labels read
Can you crush Phenytoin?
Swallow whole — the label says not to crush or chew it · Dilantin Infatabs
“DILANTIN INFATABS can be either chewed thoroughly before being swallowed or swallowed whole.” label ↗
50 labels read
Can you crush Piroxicam?
The label allows it, in the terms quoted · Piroxicam
“If desired, the daily dose may be divided.” label ↗
17 labels read
Can you crush Pomalidomide?
Swallow whole — the label says not to crush or chew it · Pomalidomide
“Do not break, chew, or open the capsules.” label ↗
7 labels read
Can you crush Posaconazole?
Swallow whole — the label says not to crush or chew it · posaconazole
“Do not divide, crush, or chew.” label ↗
34 labels read
Can you crush Pramipexole?
Swallow whole — the label says not to crush or chew it · Pramipexole dihydrochloride
“Tablets must be swallowed whole and must not be chewed, crushed, or divided.” label ↗
37 labels read
Can you crush Prednisolone?
Swallow whole — the label says not to crush or chew it · Orapred ODT
“Do not break or use partial Orapred ODT tablets.” label ↗
50 labels read
Can you crush Prednisone?
Swallow whole — the label says not to crush or chew it · Prednisone delayed release
“Prednisone delayed-release tablets should be swallowed whole and not broken, divided, or chewed.” label ↗
50 labels read
Can you crush Pregabalin?
Swallow whole — the label says not to crush or chew it · Pregabalin Extended Release
“It should be swallowed whole and should not be split, crushed, or chewed.” label ↗
50 labels read
Can you crush Propafenone?
Swallow whole — the label says not to crush or chew it · Propafenone Hydrochloride
“Do not crush or further divide the contents of the capsule.” label ↗
28 labels read
Can you crush Quetiapine?
Swallow whole — the label says not to crush or chew it · Quetiapine Extended Release
“Swallow tablets whole and do not split, chew or crush.” label ↗
50 labels read
Can you crush Rabeprazole?
Swallow whole — the label says not to crush or chew it · Rabeprazole Sodium
“Do not chew, crush or split tablets.” label ↗
37 labels read
Can you crush Raltegravir?
Swallow whole — the label says not to crush or chew it · ISENTRESS
“ISENTRESS film-coated tablets must be swallowed whole.” label ↗
It depends on what you mean — read the sentence · ISENTRESS
“ISENTRESS chewable tablets may be chewed or swallowed whole.” label ↗
The label allows it, in the terms quoted · ISENTRESS
“Additionally, the 25 mg chewable tablet may be crushed.” label ↗
5 labels read
Can you crush Ramelteon?
Swallow whole — the label says not to crush or chew it · Ramelteon
“Do not break the tablet; it should be swallowed whole.” label ↗
41 labels read
Can you crush Ranolazine?
Swallow whole — the label says not to crush or chew it · ASPRUZYO SPRINKLE
“Do not crush or chew the granules.” label ↗
32 labels read
Can you crush Rilpivirine?
Swallow whole — the label says not to crush or chew it · EDURANT
“Do not crush, chew, or swallow whole EDURANT PED tablets for oral suspension.” label ↗
9 labels read
Can you crush Risedronate?
Swallow whole — the label says not to crush or chew it · Atelvia
“Do not chew, cut, or crush Atelvia tablets.” label ↗
13 labels read
Can you crush Rivaroxaban?
Swallow whole — the label says not to crush or chew it · Xarelto
“For children who are unable to swallow whole tablets, XARELTO oral suspension may be used.” label ↗
It depends on what you mean — read the sentence · RIVAROXABAN
“Options For adult patients who are unable to swallow whole tablets, rivaroxaban tablets may be crushed and mixed with applesauce immediately prior to use and administered orally.” label ↗
The label allows it, in the terms quoted · RIVAROXABAN
“NG) tube or gastric feeding tube: After confirming gastric placement of the tube, rivaroxaban tablets (all strengths) may be crushed and suspended in 50 mL of water and administered via an NG tube or gastric feeding tube.” label ↗
27 labels read
Can you crush Rivastigmine?
Swallow whole — the label says not to crush or chew it · Rivastigmine
“Figure C • Do not cut or fold the rivastigmine transdermal system itself.” label ↗
29 labels read
Can you crush Rosuvastatin?
Swallow whole — the label says not to crush or chew it · Rosuvastatin Calcium
“The tablet should be swallowed whole.” label ↗
50 labels read
Can you crush Sapropterin?
Swallow whole — the label says not to crush or chew it · Kuvan
“Advise patients and caregivers: KUVAN tablets can be swallowed whole, dissolved in water or apple juice, or crushed and mixed with a small amount of soft food such as apple sauce or pudding.” label ↗
16 labels read
Can you crush Saxagliptin?
Swallow whole — the label says not to crush or chew it · Saxagliptin
“Do not cut, crush, or chew saxagliptin tablets.” label ↗
6 labels read
Can you crush Scopolamine?
Swallow whole — the label says not to crush or chew it · Scopolamine
“Do not cut the transdermal system.” label ↗
25 labels read
Can you crush Selegiline?
Swallow whole — the label says not to crush or chew it · EMSAM
“Do not cut the EMSAM transdermal system into smaller portions.” label ↗
15 labels read
Can you crush Selexipag?
Swallow whole — the label says not to crush or chew it · UPTRAVI
“Do not split or crush the tablets.” label ↗
3 labels read
Can you crush Sirolimus?
Swallow whole — the label says not to crush or chew it · sirolimus
“Tablets should not be crushed, chewed or split.” label ↗
26 labels read
Can you crush Solifenacin?
Swallow whole — the label says not to crush or chew it · VESIcare
“VESIcare should be taken with water and swallowed whole.” label ↗
35 labels read
Can you crush Tacrolimus?
Swallow whole — the label says not to crush or chew it · Envarsus XR
“Do not chew, divide or crush tablet.” label ↗
47 labels read
Can you crush Tadalafil?
Swallow whole — the label says not to crush or chew it · tadalafil
“Do not split tadalafil tablets; entire dose should be taken.” label ↗
50 labels read
Can you crush Tafenoquine?
Swallow whole — the label says not to crush or chew it · Arakoda
“Do not break, crush or chew the tablets.” label ↗
3 labels read
Can you crush Tamsulosin?
Swallow whole — the label says not to crush or chew it · Tamsulosin Hydrochloride
“Tamsulosin capsules should not be crushed, chewed or opened.” label ↗
50 labels read
Can you crush Temozolomide?
Swallow whole — the label says not to crush or chew it · TEMOZOLOMIDE
“Advise patients that temozolomide capsules should be swallowed whole and NEVER CHEWED.” label ↗
16 labels read
Can you crush Tinidazole?
The label allows it, in the terms quoted · Tindazole
“Compounding of the Oral Suspension For those unable to swallow tablets, tinidazole tablets may be crushed in artificial cherry syrup to be taken with food.” label ↗
6 labels read
Can you crush Tiopronin?
The label allows it, in the terms quoted · Thiola EC
“THIOLA EC can be crushed and mixed with applesauce.” label ↗
9 labels read
Can you crush Tiotropium?
Swallow whole — the label says not to crush or chew it · Tiotropium Bromide
“See Figure G) Remove the tiotropium bromide inhalation powder capsule from the blister: Do not cut the foil or use sharp instruments to take out the tiotropium bromide inhalation powder capsule from the blister.” label ↗
6 labels read
Can you crush Tofacitinib?
Swallow whole — the label says not to crush or chew it · Tofacitinib
“Do not crush, split, or chew the extended-release tablets [see Clinical Pharmacology.” label ↗
28 labels read
Can you crush Tolterodine?
Swallow whole — the label says not to crush or chew it · Tolterodine Tartrate
“DOSAGE AND ADMINISTRATION 4 mg capsules taken orally once daily with water and swallowed whole.” label ↗
22 labels read
Can you crush Topiramate?
Swallow whole — the label says not to crush or chew it · QUDEXY XR
“Capsules may be swallowed whole or opened and sprinkled on a spoonful of soft food.” label ↗
50 labels read
Can you crush Topotecan?
Swallow whole — the label says not to crush or chew it · HYCAMTIN
“Do not chew, crush, or divide the capsules.” label ↗
7 labels read
Can you crush Tramadol?
Swallow whole — the label says not to crush or chew it · TRAMADOL HYDROCHLORIDE
“The tablets should not be chewed, crushed, or split.” label ↗
The label allows it, in the terms quoted · Tramadol Hydrochloride
“Tramadol hydrochloride tablets 100 mg is a scored tablet and can be split into two halves for 50 mg dose titration or administered as a whole tablet for 100 mg dose.” label ↗
50 labels read
Can you crush Tranexamic Acid?
Swallow whole — the label says not to crush or chew it · Tranexamic Acid
“Swallow tablets whole; do not chew or break apart.” label ↗
48 labels read
Can you crush Trazodone?
Swallow whole — the label says not to crush or chew it · Trazodone Hydrochloride
“Tablets should be swallowed whole or broken in half along the score line.” label ↗
50 labels read
Can you crush Treprostinil?
Swallow whole — the label says not to crush or chew it · Orenitram
“Do not split, chew, crush, or break.” label ↗
9 labels read
Can you crush Tretinoin?
Swallow whole — the label says not to crush or chew it · Tretinoin
“Do not chew, dissolve, or open capsule.” label ↗
50 labels read
Can you crush Trientine?
Swallow whole — the label says not to crush or chew it · Trientine Hydrochloride
“The capsules should be swallowed whole with water and should not be opened or chewed.” label ↗
8 labels read
Can you crush Trihexyphenidyl?
The label allows it, in the terms quoted · Trihexyphenidyl Hydrochloride
“High doses (>10 mg daily) may be divided into 4 parts, with 3 doses administered at mealtimes and the fourth at bedtime.” label ↗
13 labels read
Can you crush Valganciclovir?
Swallow whole — the label says not to crush or chew it · Valcyte
“Do not break or crush VALCYTE tablets.” label ↗
27 labels read
Can you crush Valproic Acid?
Swallow whole — the label says not to crush or chew it · Valproic
“Valproic Acid capsules should be swallowed whole without chewing to avoid local irritation of the mouth and throat.” label ↗
23 labels read
Can you crush Venlafaxine?
Swallow whole — the label says not to crush or chew it · Venlafaxine Hydrochloride
“Do not divide, crush, chew, or place in water.” label ↗
50 labels read
Can you crush Verapamil?
Swallow whole — the label says not to crush or chew it · Verapamil Hydrochloride
“Verapamil Hydrochloride Extended-release Capsules (PM) SHOULD NOT BE CRUSHED OR CHEWED.” label ↗
50 labels read
Can you crush Zileuton?
Swallow whole — the label says not to crush or chew it · Zileuton
“Tablets should not be chewed, cut or crushed.” label ↗
6 labels read
Can you crush Ziprasidone?
Swallow whole — the label says not to crush or chew it · ziprasidone
“Do not chew, crush, or open the capsules.” label ↗
41 labels read
Can you crush Zolmitriptan?
Swallow whole — the label says not to crush or chew it · Zolmitriptan OD
“Do not break zolmitriptan orally disintegrating tablets.” label ↗
27 labels read
Can you crush Zolpidem?
Swallow whole — the label says not to crush or chew it · ZOLPIDEM TARTRATE
“Tablets to be swallowed whole, not to be crushed, divided or chewed.” label ↗
50 labels read
Can you crush Zonisamide?
Swallow whole — the label says not to crush or chew it · Zonisamide
“Capsules should be swallowed whole.” label ↗
34 labels read
Frequently asked questions
Why not just publish a 'do not crush' list?
Because a list of drug names cannot express the answer. Metoprolol succinate extended-release is, in its label's own words, "scored and can be divided; however, do not crush or chew the whole or half tablet" — permitted and forbidden in the same sentence, depending on what you are doing to it. And the immediate-release version of the same drug is a different product with different instructions. Quoting the label keeps that intact; a name on a list loses it.
Why does crushing an extended-release tablet matter so much?
Because the coating or matrix is what meters the dose out over the day. Crush it and the entire day's dose is released at once — which for an opioid, a heart-rate drug or an ADHD stimulant is the difference between a dose and an overdose. That mechanism, not the molecule, is why the instruction exists.
What if a drug isn't listed here?
It means none of the labels we read prints an instruction about crushing or splitting. Those pages exist and say so with the number of labels checked, but they are not submitted for indexing because the text is necessarily the same for every such drug. Absence of a restriction is also not a technique guide — an unscored tablet still splits unevenly.
I can't swallow tablets. What should I do?
Ask the prescriber or pharmacist before altering anything. Most drugs that cannot be crushed exist in another form — a liquid, a dispersible tablet, a patch, or an immediate-release version taken more often — and switching is usually straightforward.
Reference information quoted from FDA labels, not medical advice. Never alter a tablet against its label to make it easier to take — an alternative form usually exists, and a pharmacist can arrange it.