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Which medications are safe in pregnancy?

What each drug’s FDA label actually states in its Pregnancy Risk Summary (§8.1) — transcribed, not a secondhand verdict — grouped by how the label reads. Every one of these is a decision to make with your prescriber, never alone.

Two things to hold onto. First, “no clear risk reported” is not a guarantee of safety — no drug is tested in pregnancy the way it is in other adults. Second, an untreated condition can itself harm a pregnancy, so stopping a medication is not automatically the safe choice. This is exactly the kind of trade-off a prescriber weighs.

By the pharmaranks editorial teamReviewed against the FDA drug labels (DailyMed, §8.1) sourcesUpdated Jul 21, 2026How we research

Breastfeeding is a separate question with a separate evidence base — see medicines and breastfeeding, quoted from the NIH’s LactMed database. A drug the label treats cautiously in pregnancy is not thereby a problem while nursing, and the reverse is just as true.

Contraindicated in pregnancy

Known fetal risk

Avoid unless needed

No clear risk reported

Insufficient data

Each entry is transcribed from that drug’s FDA-approved label §8.1; “insufficient data” is never rounded up to “safe.” General reference information, not medical advice. Whether to use any drug in pregnancy is a decision for you and your prescriber. In an emergency call 911; for pregnancy-medication questions, MotherToBaby (1-866-626-6847) is a free US service.