Plain-English, source-backed summaries of drugs under active mass-tort litigation — what the lawsuits allege, the FDA's labeling actions, and where each case stands. Information only, not legal or medical advice.
GLP-1 drugs such as Ozempic and Wegovy face thousands of lawsuits alleging severe gastrointestinal injury (gastroparesis, intestinal blockage) and, in a separate federal case, permanent vision loss (NAION).
Depo-Provera, the long-acting birth-control shot, faces thousands of lawsuits alleging that long-term use raises the risk of meningioma (a brain tumor). The FDA has added a meningioma warning to the label.
Suboxone sublingual film faces a mass tort alleging that its acidic formulation causes severe tooth decay, erosion, and tooth loss. The FDA added a dental-problems warning to mouth-dissolved buprenorphine medicines in 2022.
Tepezza, an infusion for thyroid eye disease, faces lawsuits alleging it caused permanent hearing loss and tinnitus that the label failed to adequately warn about.
Certain generic valsartan blood-pressure pills were recalled after being found contaminated with NDMA, a probable carcinogen. Lawsuits allege the contamination caused cancer. (Brand-name Diovan was not part of the recall.)
Elmiron, prescribed for interstitial cystitis (bladder pain), faces lawsuits alleging that long-term use causes pigmentary maculopathy — a form of retinal damage and vision loss.