Depo-Provera Lawsuit
medroxyprogesterone acetate · Pfizer · updated June 2026
Depo-Provera, the long-acting birth-control shot, faces thousands of lawsuits alleging that long-term use raises the risk of meningioma (a brain tumor). The FDA has added a meningioma warning to the label.
This page is general information about ongoing litigation and FDA safety actions — not medical or legal advice, and not a statement that Depo-Provera caused any injury. Allegations described here are claims that have not been proven in court. Always consult a licensed professional.
What the lawsuits allege
Plaintiffs allege Pfizer failed to warn that repeated, long-term use of the medroxyprogesterone acetate shot increases the risk of developing a meningioma.
- Meningioma (brain tumor)
FDA action
The FDA updated the Depo-Provera label to add a meningioma warning, reflecting cases reported with long-term use.
Verify against the current FDA-approved label: Depo-Provera label on DailyMed (U.S. NLM).
Where the litigation stands
As of mid-2026, several thousand meningioma claims are consolidated in a federal MDL. Bellwether trial dates have been in flux — treat any specific date as subject to change — and reports in June 2026 indicate Pfizer agreed to settle claims filed in the MDL.
Case counts and MDL status are published by the U.S. Judicial Panel on Multidistrict Litigation — JPML pending MDLs. Any figure not on the court record is attributed to the secondary legal-press links below.
Who may be affected
The Depo-Provera lawsuits are brought by people who say they used Depo-Provera (medroxyprogesterone acetate) and were later diagnosed with one or more of the alleged injuries above. Whether any individual situation could support a claim depends on the specific facts, the medical records, and each state's filing deadline (statute of limitations) — which can expire, so timing matters. Only a licensed attorney can evaluate a specific case. This page is general information, not legal advice.
Frequently asked
- What is the Depo-Provera lawsuit about?
- Plaintiffs allege Pfizer failed to warn that repeated, long-term use of the medroxyprogesterone acetate shot increases the risk of developing a meningioma. As of mid-2026, several thousand meningioma claims are consolidated in a federal MDL. Bellwether trial dates have been in flux — treat any specific date as subject to change — and reports in June 2026 indicate Pfizer agreed to settle claims filed in the MDL.
- What injuries are alleged in the Depo-Provera lawsuits?
- Lawsuits allege meningioma (brain tumor). These are allegations; a court has not found that Depo-Provera causes them.
- Has the FDA acted on Depo-Provera?
- The FDA updated the Depo-Provera label to add a meningioma warning, reflecting cases reported with long-term use.
- Is there a deadline to file a Depo-Provera lawsuit?
- Yes — every state sets a filing deadline (statute of limitations) for product-injury claims, often running from the date of injury or diagnosis, and once it passes a claim is usually barred. The exact window varies by state and circumstances, so anyone considering a claim should check with a licensed attorney promptly. This is general information, not legal advice.