Best Azole Antifungal for tinea pedis
Top-rated pick: Clotrimazole — pharmaranks score 70/100, the highest of the 13 Azole Antifungal drugs used for tinea pedis, ranked by our independent FDA recall-safety score. Compare them with all treatments for tinea pedis or the full Azole Antifungal class. Not medical advice — always consult a professional.
Quick answer: Of the 13 azole antifungal drugs we rate for tinea pedis, 7 are available as lower-cost generics, and most are topical. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for tinea pedis; the right choice depends on your situation, so confirm it with your prescriber.
How azole antifungal work
Azole antifungals block a fungal enzyme (lanosterol 14-alpha-demethylase) that the fungus needs to make ergosterol, a key building block of its cell membrane. Without enough ergosterol the membrane becomes leaky and unstable, which stops the fungus from growing and can cause it to break apart and die.
Source: Antifungal Ergosterol Synthesis Inhibitors — StatPearls, NCBI Bookshelf (NIH)
Top azole antifungal for tinea pedis: 1. Clotrimazole · 2. Monistat 3 · 3. Monistat 3 Combination Pack
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | 70/100 | Prescription | Topical | Generic | $0 | View → | |
| 2 | 70/100 | Over-the-counter | Kit | No data | — | View → | |
| 3 | 70/100 | Over-the-counter | Kit | No data | — | View → | |
| 4 | 70/100 | Over-the-counter | Kit | No data | — | View → | |
| 5 | 70/100 | Over-the-counter | Suppository | No data | — | View → | |
| 6 | 70/100 | Over-the-counter | Suppository | No data | — | View → | |
| 7 | Not yet rated | Prescription | Liquid | Generic | $0 | View → | |
| 8 | Not yet rated | Prescription | Topical | Generic | $0 | View → | |
| 9 | Not yet rated | Prescription | Solution | No data | — | View → | |
| 10 | Not yet rated | Over-the-counter | Spray/Inhaler | Generic | $0 | View → |
Full ranking · 13 drugs
clotrimazole
PrescriptionFDA-sourced
Clotrimazole is an azole antifungal used to treat Cutaneous Candidiasis, Oral Candidiasis, Vulvovaginal Candidiasis, Tinea Pedis.
Pharmacy pays
From ~$0.09· 6 formsmonistat 3
Over-the-counterFDA-sourced
Monistat 3 (Miconazole Nitrate) is an azole antifungal used to treat Aspergillosis, Cutaneous Candidiasis, Vulvovaginal Candidiasis, Tinea Pedis.
monistat 3 combination pack
Over-the-counterFDA-sourced
Monistat 3 Combination Pack (Miconazole Nitrate) is an azole antifungal used to treat Aspergillosis, Cutaneous Candidiasis, Vulvovaginal Candidiasis, Tinea Pedis.
monistat 3 combination pack (prefilled)
Over-the-counterFDA-sourced
Monistat 3 Combination Pack (Prefilled) (Miconazole Nitrate) is an azole antifungal used to treat Aspergillosis, Cutaneous Candidiasis, Vulvovaginal Candidiasis, Tinea Pedis.
monistat 7
Over-the-counterFDA-sourced
Monistat 7 (Miconazole Nitrate) is an azole antifungal used to treat Aspergillosis, Cutaneous Candidiasis, Vulvovaginal Candidiasis, Tinea Pedis.
monistat 7 combination pack
Over-the-counterFDA-sourced
Monistat 7 Combination Pack (Miconazole Nitrate) is an azole antifungal used to treat Aspergillosis, Cutaneous Candidiasis, Vulvovaginal Candidiasis, Tinea Pedis.
clotic
PrescriptionFDA-sourced
Clotic (Clotrimazole) is an azole antifungal used to treat Cutaneous Candidiasis, Oral Candidiasis, Vulvovaginal Candidiasis, Tinea Pedis.
Pharmacy pays
From ~$0.09· 6 formsecoza
PrescriptionFDA-sourced
Ecoza (Econazole Nitrate) is an azole antifungal used to treat Cutaneous Candidiasis, Tinea Pedis, Tinea Versicolor.
Pharmacy pays
$0.36 /g
Save up to 65% in classexelderm
PrescriptionFDA-sourced
Exelderm (Sulconazole Nitrate) is an azole antifungal used to treat Cutaneous Candidiasis, Tinea Pedis, Tinea Versicolor.
Price varies
lotrimin af
Over-the-counterFDA-sourced
Lotrimin Af (Clotrimazole) is an azole antifungal used to treat Cutaneous Candidiasis, Oral Candidiasis, Vulvovaginal Candidiasis, Tinea Pedis.
Pharmacy pays
From ~$0.09· 6 formsmycelex
Over-the-counterFDA-sourced
Mycelex (Clotrimazole) is an azole antifungal used to treat Cutaneous Candidiasis, Oral Candidiasis, Vulvovaginal Candidiasis, Tinea Pedis.
Pharmacy pays
From ~$0.09· 6 formsoravig
PrescriptionFDA-sourced
Oravig (Miconazole) is an azole antifungal used to treat Aspergillosis, Cutaneous Candidiasis, Vulvovaginal Candidiasis, Tinea Pedis.
Pharmacy pays
From ~$0.12· 7 formstrivagizole 3
Over-the-counterFDA-sourced
Trivagizole 3 (Clotrimazole) is an azole antifungal used to treat Cutaneous Candidiasis, Oral Candidiasis, Vulvovaginal Candidiasis, Tinea Pedis.
Pharmacy pays
From ~$0.09· 6 formsFrequently asked
- What is the best azole antifungal for tinea pedis?
- By our independent recall-safety rating — not an efficacy measure — clotrimazole ranks highest among Azole Antifungal drugs used for tinea pedis. Always consult a professional.
- Which azole antifungal drugs treat tinea pedis?
- pharmaranks lists 13 Azole Antifungal products used for tinea pedis, per NIH RxClass drug-classification data — each independently rated and ranked above.
- How are these ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.