clotrimazole

What is Clotrimazole?

From the FDA label:Clotrimazole Cream USP 1% contains clotrimazole, a synthetic antifungal agent having the chemical name {1-(o-Chloro-α, α-diphenylbenzyl)imidazole}; the molecular formula C 22 H 17 ClN 2 ; a molecular weight of 344.84; and the structural formula: Clotrimazole is an odorless, white crystalline substance. It is practically insoluble in water, sparingly soluble in ether and very soluble in polyethylene glycol 400, ethanol and chloroform. Each gram of Clotrimazole cream contains 10 mg clotrimazole, dispersed in a vanishing cream base of sorbitan monostearate, polysorbate 60, cetyl esters wax, cetostearyl alcohol, octyldodecanol, purified water, and benzyl alcohol (1%) as preservative. StructuralFormula

How to use

Clotrimazole is sold in more than one form (Topical, Lozenge, Solution and Spray/Inhaler), and each is dosed differently. The instructions below come from the FDA label for application ANDA078338 — follow the label that came with the product you were actually prescribed.

Side effects

Warnings

Who should not take Clotrimazole

Overdose — what happens if you take too much

Interactions

Frequently asked questions

What does Clotrimazole treat?

Clotrimazole (Clotrimazole) may be used to treat cutaneous candidiasis, oral candidiasis, vulvovaginal candidiasis, tinea pedis, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.

How does Clotrimazole work?

Clotrimazole is a azole antifungal. Azole antifungals block a fungal enzyme (lanosterol 14-alpha-demethylase) that the fungus needs to make ergosterol, a key building block of its cell membrane. Without enough ergosterol the membrane becomes leaky and unstable, which stops the fungus from growing and can cause it to break apart and die.

How is Clotrimazole rated?

pharmaranks gives Clotrimazole a composite score of 3.5 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.

How much does Clotrimazole cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.21 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Clotrimazole?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Clotrimazole. To pay less, Clotrimazole is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Clotrimazole?

Clotrimazole is marketed by Fougera Pharms. You can see Fougera Pharms's full profile, rating, and other products on pharmaranks.

Is Clotrimazole a brand-name or generic drug?

Clotrimazole is a generic medication; its active ingredient is Clotrimazole. Generics contain the same active ingredient as the brand-name original and are usually lower cost.

Is Clotrimazole available over the counter?

No. Clotrimazole is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Clotrimazole come in?

Clotrimazole is currently marketed as topical, lozenge, solution and spray/inhaler, per the FDA's National Drug Code Directory.

What class of drug is Clotrimazole?

Clotrimazole is classified as azole antifungal, per the FDA's Established Pharmacologic Class.

Is Clotrimazole FDA-registered?

Clotrimazole is on record with the U.S. FDA under application number ANDA078338. You can verify this on its official FDA label.

Has Clotrimazole been recalled by the FDA?

Clotrimazole has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.

Is Clotrimazole safe?

There's no single safe-or-not verdict. pharmaranks gives Clotrimazole a recall-safety score of 70/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

What are the side effects of Clotrimazole?

Clotrimazole's side effects are taken directly from its FDA label. From the label: The following adverse reactions have been reported in connection with the use of this product: erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning, and general irritation of the skin. Both common and serious reactions are documented in full on this page. This is general reference from the FDA, not medical advice — always consult a professional.