clotrimazole
Pharmaranks rates Clotrimazole 3.6/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Clotrimazole is an azole antifungal used to treat Cutaneous Candidiasis, Oral Candidiasis, Vulvovaginal Candidiasis, Tinea Pedis.
Azole Antifungal · by Fougera Pharms
Generic of Clotic
Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →
Key facts
- Active ingredient
- Clotrimazole
- Drug class
- Azole Antifungal
- Form
- Topical, Lozenge, Solution, Spray/Inhaler
- Strength
- Clotrimazole 1%
- Type
- Prescription (Rx)
- Brand or generic
- Generic
- Manufacturer
- Fougera Pharms
- What the pharmacy pays
- ~$0.21 per ml — not your price
- FDA application
- ANDA078338
Drug class
How this class works, per Antifungal Ergosterol Synthesis Inhibitors — StatPearls, NCBI Bookshelf (NIH).
May treat (source: NIH RxClass)
See how Clotrimazole ranks — best-rated azole antifungal for:
Dosage forms
Topical, Lozenge, Solution and Spray/Inhaler
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Clotrimazole treat?
- Clotrimazole (Clotrimazole) may be used to treat cutaneous candidiasis, oral candidiasis, vulvovaginal candidiasis, tinea pedis, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How does Clotrimazole work?
- Clotrimazole is a azole antifungal. Azole antifungals block a fungal enzyme (lanosterol 14-alpha-demethylase) that the fungus needs to make ergosterol, a key building block of its cell membrane. Without enough ergosterol the membrane becomes leaky and unstable, which stops the fungus from growing and can cause it to break apart and die.
- How is Clotrimazole rated?
- pharmaranks gives Clotrimazole a composite score of 3.6 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
- How much does Clotrimazole cost?
- Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.21 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
- Is there a coupon or discount for Clotrimazole?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Clotrimazole. To pay less, Clotrimazole is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Clotrimazole?
- Clotrimazole is marketed by Fougera Pharms. You can see Fougera Pharms's full profile, rating, and other products on pharmaranks.
- Is Clotrimazole a brand-name or generic drug?
- Clotrimazole is a generic medication; its active ingredient is Clotrimazole. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
- Is Clotrimazole available over the counter?
- No. Clotrimazole is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Clotrimazole come in?
- Clotrimazole is currently marketed as topical, lozenge, solution and spray/inhaler, per the FDA's National Drug Code Directory.
- What class of drug is Clotrimazole?
- Clotrimazole is classified as azole antifungal, per the FDA's Established Pharmacologic Class.
- Is Clotrimazole FDA-registered?
- Clotrimazole is on record with the U.S. FDA under application number ANDA078338. You can verify this on its official FDA label.
- Has Clotrimazole been recalled by the FDA?
- Clotrimazole has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
- Is Clotrimazole safe?
- There's no single safe-or-not verdict. pharmaranks gives Clotrimazole a recall-safety score of 72/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about Clotrimazole
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 15,513 reports naming Clotrimazole, and the FDA flagged 72% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- nausea1,032 reports
- fatigue939 reports
- headache921 reports
- dyspnoea866 reports
- macular degeneration818 reports
- diarrhoea802 reports
- rash631 reports
- anxiety591 reports
Read these as a signal, not a rate. A report does not mean Clotrimazole caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 25, 2026.
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clotrimazole
72/100