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xolegel

Xolegel (Ketoconazole) is an azole antifungal used to treat Blastomycosis, Chronic Mucocutaneous Candidiasis, Cutaneous Candidiasis, Oral Candidiasis.

Ketoconazole · by Ina Pharms

Available as a generic: Ketoconazole

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
$0.27 /g
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Key facts

Active ingredient
Ketoconazole
Form
Topical
Strength
Ketoconazole 2%
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Ina Pharms
What the pharmacy pays
~$0.27 per gm — not your price
FDA application
NDA021946
Availability
Discontinued (per FDA)

Drug class

How this class works, per Antifungal Ergosterol Synthesis Inhibitors — StatPearls, NCBI Bookshelf (NIH).

May treat (source: NIH RxClass)

Dosage forms

Topical

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Xolegel treat?
Xolegel (Ketoconazole) may be used to treat blastomycosis, chronic mucocutaneous candidiasis, cutaneous candidiasis, oral candidiasis, vulvovaginal candidiasis, coccidioidomycosis, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Xolegel work?
Xolegel is a azole antifungal. Azole antifungals block a fungal enzyme (lanosterol 14-alpha-demethylase) that the fungus needs to make ergosterol, a key building block of its cell membrane. Without enough ergosterol the membrane becomes leaky and unstable, which stops the fungus from growing and can cause it to break apart and die.
How much does Xolegel cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.27 per gm, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Xolegel?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Xolegel. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Xolegel?
Xolegel is marketed by Ina Pharms. You can see Ina Pharms's full profile, rating, and other products on pharmaranks.
Is Xolegel a brand-name or generic drug?
Xolegel is a brand-name product with the active ingredient Ketoconazole. Lower-cost generic equivalents containing Ketoconazole are available — ask your pharmacist.
Is Xolegel available over the counter?
No. Xolegel is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Xolegel come in?
Xolegel is currently marketed as topical, per the FDA's National Drug Code Directory.
What class of drug is Xolegel?
Xolegel is classified as azole antifungal, per the FDA's Established Pharmacologic Class.
Is Xolegel FDA-registered?
Xolegel is on record with the U.S. FDA under application number NDA021946. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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