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Pharmaranks rates Prevacid 24 Hr 3.2/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Prevacid 24 Hr (Lansoprazole) is a proton pump inhibitor used to treat Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux, Stomach Ulcer.

Lansoprazole · by Perrigo

Available as a generic: Lansoprazole

64/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
~$5.10 /30
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Key facts

Active ingredient
Lansoprazole
Form
Capsule, delayed release
Strength
Lansoprazole 15MG
Type
Over-the-counter (OTC)
Brand or generic
Brand-name
Manufacturer
Perrigo
Half-life
about 1.5 hours (mean, ±1.0) in healthy adults — the label states the plasma elimination half-life is less than two hours (how long it stays in your system)
What the pharmacy pays
~$5.10 for 30 — not your price
FDA application
NDA022327

How long does Lansoprazole stay in your body?

The elimination half-life of lansoprazole is about 1.5 hours (mean, ±1.0) in healthy adults — the label states the plasma elimination half-life is less than two hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the terminal plasma elimination half-life; the label reports a single half-life, not separate distribution/elimination phases. Important: the short half-life does NOT reflect duration of effect — lansoprazole is a proton-pump inhibitor whose acid-suppressing effect lasts more than 24 hours even though the drug clears from plasma in under 2 hours, so the label explicitly warns the half-life does not reflect its duration of acid suppression. No long-lasting active metabolite: the two identified plasma metabolites (hydroxylated sulfinyl and sulfone) have very little or no antisecretory activity, and the active species that block the proton pump are not present in the systemic circulation. Population changes per the label: in older adults clearance falls and the elimination half-life rises roughly 50%–100% (mean 1.9–2.9 hours); in hepatic impairment it is prolonged from 1.5 hours to about 4 hours (Child-Pugh A) or 5 hours (Child-Pugh B), with much larger AUC increases in cirrhosis; in renal impairment the elimination half-life is SHORTENED (not lengthened) and no dosage change is needed.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Lansoprazole delayed-release capsules — DailyMed label, §12.3 Pharmacokinetics.

Drug class

How this class works, per Proton Pump Inhibitors (PPI) - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

Dosage forms

Capsule, delayed release

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Prevacid 24 Hr treat?
Prevacid 24 Hr (Lansoprazole) may be used to treat duodenal ulcer, esophagitis, gastroesophageal reflux, stomach ulcer, zollinger-ellison syndrome, helicobacter infections, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Prevacid 24 Hr work?
Prevacid 24 Hr is a proton pump inhibitor. Proton pump inhibitors block the H+/K+ ATPase 'proton pump' in the stomach's acid-making cells, the final step in producing stomach acid. By binding this pump, they sharply and lastingly cut acid output, easing heartburn and helping ulcers heal.
How is Prevacid 24 Hr rated?
pharmaranks gives Prevacid 24 Hr a composite score of 3.2 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
How much does Prevacid 24 Hr cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $5.10 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Prevacid 24 Hr?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Prevacid 24 Hr. To pay less, look for a store-brand version with the same active ingredient (Lansoprazole), which is typically cheaper, and compare unit prices. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Prevacid 24 Hr?
Prevacid 24 Hr is marketed by Perrigo. You can see Perrigo's full profile, rating, and other products on pharmaranks.
Is Prevacid 24 Hr a brand-name or generic drug?
Prevacid 24 Hr is a brand-name product with the active ingredient Lansoprazole. Lower-cost generic equivalents containing Lansoprazole are available — ask your pharmacist.
Is Prevacid 24 Hr available over the counter?
Yes. Prevacid 24 Hr is an over-the-counter (OTC) product — you can buy it without a prescription. Follow the label directions and ask a pharmacist if you're unsure whether it's right for you.
What forms does Prevacid 24 Hr come in?
Prevacid 24 Hr is currently marketed as capsule, delayed release, per the FDA's National Drug Code Directory.
What class of drug is Prevacid 24 Hr?
Prevacid 24 Hr is classified as proton pump inhibitor, per the FDA's Established Pharmacologic Class.
Is Prevacid 24 Hr FDA-registered?
Prevacid 24 Hr is on record with the U.S. FDA under application number NDA022327. You can verify this on its official FDA label.
Has Prevacid 24 Hr been recalled by the FDA?
Prevacid 24 Hr has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Prevacid 24 Hr safe?
There's no single safe-or-not verdict. pharmaranks gives Prevacid 24 Hr a recall-safety score of 64/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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