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Best treatments for stomach ulcer

12 products may treat stomach ulcer, spanning FDA drug classes such as aluminum complex, histamine-2 receptor antagonist, proton pump inhibitor. The current highest-rated option is carafate. Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.

Quick answer: Of the 12 drugs we list for stomach ulcer, 11 are available as lower-cost generics, spanning classes such as aluminum complex, histamine-2 receptor antagonist, proton pump inhibitor. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for stomach ulcer — so confirm the right choice with your prescriber.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Top-rated picks for stomach ulcer: 1. Carafate · 2. Famotidine · 3. Pepcid Ac

Top-rated treatments for stomach ulcer, ranked by pharmaranks score
#DrugRatingPharmacy pays
172/100$5View →
270/100$2View →
370/100$2View →
470/100View →
570/100$10View →
664/100$5View →
762/100$5View →
8Not yet rated$7View →
9Not yet rated$10View →
10Not yet rated$7View →

Full ranking · 12 treatments

ABBVIE logo

carafate

PrescriptionFDA-sourced

72/100

Carafate (Sucralfate) is an aluminum complex used to treat Duodenal Ulcer, Esophagitis, Gastritis, Pneumonia.

(6 data points)
aluminum complexduodenal ulceresophagitis

Pharmacy pays

From ~$3.58/30· 2 forms
View details →
#1 of 11 in Histamine-2 Receptor Antagonist

famotidine

PrescriptionFDA-sourced

70/100

Famotidine is a histamine-2 receptor antagonist used to treat Duodenal Ulcer, Dyspepsia, Peptic Esophagitis, Gastroesophageal Reflux.

(1 data points)
histamine-2 receptor antagonistduodenal ulcerdyspepsia

Pharmacy pays

From ~$0.91/30· 5 forms
View details →
#1 of 11 in Histamine-2 Receptor Antagonist

pepcid ac

Over-the-counterFDA-sourced

70/100

Pepcid Ac (Famotidine) is a histamine-2 receptor antagonist used to treat Duodenal Ulcer, Dyspepsia, Peptic Esophagitis, Gastroesophageal Reflux.

(1 data points)
histamine-2 receptor antagonistduodenal ulcerdyspepsia

Pharmacy pays

From ~$0.91/30· 5 forms
View details →
#1 of 7 in Proton Pump Inhibitor

prilosec otc

Over-the-counterFDA-sourced

70/100

Prilosec OTC (Omeprazole Magnesium) is a proton pump inhibitor used to treat Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux, Heartburn.

(1 data points)
proton pump inhibitorduodenal ulceresophagitis
Available online
View details →
#1 of 11 in Histamine-2 Receptor Antagonist

tagamet hb

Over-the-counterFDA-sourced

70/100

Tagamet Hb (Cimetidine) is a histamine-2 receptor antagonist used to treat Duodenal Ulcer, Dyspepsia, Peptic Esophagitis, Gastroesophageal Reflux.

(9 data points)
histamine-2 receptor antagonistduodenal ulcerdyspepsia

Pharmacy pays

From ~$6.30/30· 5 forms Save up to 84% in class
View details →
PERRIGO logo

prevacid 24 hr

Over-the-counterFDA-sourced

64/100

Prevacid 24 Hr (Lansoprazole) is a proton pump inhibitor used to treat Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux, Stomach Ulcer.

(52 data points)
proton pump inhibitorduodenal ulceresophagitis

Pharmacy pays

From ~$3.22/30· 4 forms Save up to 70% in class
View details →

Frequently asked

What treats stomach ulcer?
Our catalog lists 12 products that may treat stomach ulcer, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is carafate.
What is the best-rated treatment for stomach ulcer?
By our independent recall-safety rating — not an efficacy measure — carafate ranks highest among the products we list for stomach ulcer. Always consult a professional.
How are these treatments ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
What types of drugs treat stomach ulcer?
Treatments for stomach ulcer span FDA drug classes including aluminum complex, histamine-2 receptor antagonist, proton pump inhibitor, anticholinergic, cholinergic muscarinic antagonist. Compare every option side by side, ranked by independent rating, above.

Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.