Anticholinergic drugs compared

Compare all 14 Anticholinergic drugs side by side, used for conditions such as bronchial spasm, bronchitis, pulmonary emphysema. They share one FDA-defined mechanism but differ in approved uses, prescription status, brand-vs-generic options, price, and FDA recall-safety record — which our independent rating scores. The highest-rated is atrovent hfa.

Top-rated anticholinergic: 1. Atrovent Hfa · 2. Spiriva Respimat · 3. Dicyclomine Hydrochloride

Anticholinergic drugs compared side by side, with pharmaranks' FDA recall-safety rating
Drug	Generic	Form	Status	Used for	Safety ratingFDA recall-based	Pharmacy pays
Atrovent Hfa	Ipratropium Bromide	Spray/Inhaler	Prescription	Bronchial Spasm, Bronchitis	72/100	$1
Spiriva Respimat	Tiotropium Bromide	Spray/Inhaler	Prescription	Pulmonary Emphysema, Bronchitis, Chronic	72/100	$354
Dicyclomine Hydrochloride	—	Capsule	Prescription	Irritable Bowel Syndrome	70/100	$2
Spiriva	Tiotropium Bromide	Capsule	Prescription	Pulmonary Emphysema, Bronchitis, Chronic	70/100	$354
Tudorza Pressair	Aclidinium Bromide	Powder	Prescription	Bronchial Spasm, Pulmonary Disease, Chronic Obstructive	70/100	—
Atropine Sulfate	—	Injectable	Prescription	Bradycardia, Heart Arrest	Not yet rated	$7
Benztropine Mesylate	—	Injectable	Prescription	Abnormalities, Drug-Induced, Parkinson Disease	Not yet rated	—
Cuvposa	Glycopyrrolate	Liquid	Prescription	Hyperhidrosis, Abnormalities, Drug-Induced	Not yet rated	$0
Glycopyrrolate	—	Injectable	Prescription	Hyperhidrosis, Abnormalities, Drug-Induced	Not yet rated	$0
Glyrx-Pf	Glycopyrrolate	Injectable	Prescription	Hyperhidrosis, Abnormalities, Drug-Induced	Not yet rated	$0
Isopto Atropine	Atropine Sulfate	Solution	Prescription	Bradycardia, Heart Arrest	Not yet rated	$7
Robinul	Glycopyrrolate	Tablet	Prescription	Hyperhidrosis, Abnormalities, Drug-Induced	Not yet rated	$0

The safety rating column is unique to pharmaranks — an independent 0–100 score from FDA regulatory recall data. Higher is safer. Not medical advice.

Best anticholinergic by condition

for bronchial spasm for pulmonary emphysema for vasomotor rhinitis for chronic bronchitis

Full ranking · 14 drugs

Frequently asked questions

What is the Anticholinergic drug class?

Anticholinergic is an FDA Established Pharmacologic Class (EPC) — a group of drugs that share a mechanism of action. pharmaranks lists 14 Anticholinergic products, each independently rated.

Are all Anticholinergic drugs the same?

No. Anticholinergic drugs share the same core mechanism — that is why they sit in one FDA class — but they differ in their approved uses, available forms, whether they are prescription or over-the-counter, brand-vs-generic options and price, and their FDA recall-safety record.

What conditions do Anticholinergic drugs treat?

Per NIH RxClass drug-classification data, Anticholinergic drugs are used for conditions including bronchial spasm, bronchitis, pulmonary emphysema, rhinitis, allergic, perennial, rhinitis, vasomotor, bronchitis, chronic.

Which Anticholinergic drug is best-rated?

By our independent rating, atrovent hfa currently ranks highest among Anticholinergic drugs. Ratings are based on FDA regulatory (recall-safety) data — always consult a professional.

Sources: the Anticholinergic class definition and its member drugs come from the U.S. NLM RxClass (Established Pharmacologic Class); how the class works is summarized from Muscarinic Antagonists - StatPearls - NCBI Bookshelf. Ratings are pharmaranks’ independent FDA recall-safety analysis.