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lansoprazole

Lansoprazole is a proton pump inhibitor used to treat Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux, Stomach Ulcer.

Proton Pump Inhibitor · by Sun Pharm

Generic of Prevacid 24 Hr

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
~$5.10 /30
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Key facts

Active ingredient
Lansoprazole
Form
Tablet, orally disintegrating
Strength
Lansoprazole 30MG
Type
Prescription (Rx)
Brand or generic
Generic
Manufacturer
Sun Pharm
Half-life
about 1.5 hours (mean, ±1.0) in healthy adults — the label states the plasma elimination half-life is less than two hours (how long it stays in your system)
What the pharmacy pays
~$5.10 for 30 — not your price
FDA application
ANDA091509
Availability
Discontinued (per FDA)

How long does Lansoprazole stay in your body?

The elimination half-life of lansoprazole is about 1.5 hours (mean, ±1.0) in healthy adults — the label states the plasma elimination half-life is less than two hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the terminal plasma elimination half-life; the label reports a single half-life, not separate distribution/elimination phases. Important: the short half-life does NOT reflect duration of effect — lansoprazole is a proton-pump inhibitor whose acid-suppressing effect lasts more than 24 hours even though the drug clears from plasma in under 2 hours, so the label explicitly warns the half-life does not reflect its duration of acid suppression. No long-lasting active metabolite: the two identified plasma metabolites (hydroxylated sulfinyl and sulfone) have very little or no antisecretory activity, and the active species that block the proton pump are not present in the systemic circulation. Population changes per the label: in older adults clearance falls and the elimination half-life rises roughly 50%–100% (mean 1.9–2.9 hours); in hepatic impairment it is prolonged from 1.5 hours to about 4 hours (Child-Pugh A) or 5 hours (Child-Pugh B), with much larger AUC increases in cirrhosis; in renal impairment the elimination half-life is SHORTENED (not lengthened) and no dosage change is needed.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Lansoprazole delayed-release capsules — DailyMed label, §12.3 Pharmacokinetics.

Drug class

How this class works, per Proton Pump Inhibitors (PPI) - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

Dosage forms

Tablet, orally disintegrating

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Lansoprazole treat?
Lansoprazole (Lansoprazole) may be used to treat duodenal ulcer, esophagitis, gastroesophageal reflux, stomach ulcer, zollinger-ellison syndrome, helicobacter infections, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Lansoprazole work?
Lansoprazole is a proton pump inhibitor. Proton pump inhibitors block the H+/K+ ATPase 'proton pump' in the stomach's acid-making cells, the final step in producing stomach acid. By binding this pump, they sharply and lastingly cut acid output, easing heartburn and helping ulcers heal.
How much does Lansoprazole cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $5.10 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Lansoprazole?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Lansoprazole. To pay less, Lansoprazole is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Lansoprazole?
Lansoprazole is marketed by Sun Pharm. You can see Sun Pharm's full profile, rating, and other products on pharmaranks.
Is Lansoprazole a brand-name or generic drug?
Lansoprazole is a generic medication; its active ingredient is Lansoprazole. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
Is Lansoprazole available over the counter?
No. Lansoprazole is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Lansoprazole come in?
Lansoprazole is currently marketed as tablet, orally disintegrating, per the FDA's National Drug Code Directory.
What class of drug is Lansoprazole?
Lansoprazole is classified as proton pump inhibitor, per the FDA's Established Pharmacologic Class.
Is Lansoprazole FDA-registered?
Lansoprazole is on record with the U.S. FDA under application number ANDA091509. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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