ESOMEPRAZOLE MAGNESIUM vs LANSOPRAZOLE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. ESOMEPRAZOLE MAGNESIUM and LANSOPRAZOLE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ESOMEPRAZOLE MAGNESIUM	LANSOPRAZOLE
Rating	66/100	New
Pharmacy pays	—	~$5.10 /30
Type	RX	RX
Active ingredient	ESOMEPRAZOLE MAGNESIUM	LANSOPRAZOLE
Manufacturer	Mylan	Sun Pharm
Dosage forms	Capsule, delayed release, Powder, extended release	Tablet, orally disintegrating
Drug class	Proton Pump Inhibitor	Proton Pump Inhibitor
Boxed warning	None	None
Half-life	—	about 1.5 hours (mean, ±1.0) in healthy adults — the label states the plasma elimination half-life is less than two hours
Treats	Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux	Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux

esomeprazole magnesium lansoprazole

Rating

66/100

New

Pharmacy pays

—

~$5.10 /30

Type

Active ingredient

ESOMEPRAZOLE MAGNESIUM

LANSOPRAZOLE

Manufacturer

Mylan

Sun Pharm

Dosage forms

Capsule, delayed release, Powder, extended release

Tablet, orally disintegrating

Drug class

Proton Pump Inhibitor

Boxed warning

None

Half-life

—

about 1.5 hours (mean, ±1.0) in healthy adults — the label states the plasma elimination half-life is less than two hours

Treats

Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux

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Frequently asked questions

What is the difference between Esomeprazole Magnesium and Lansoprazole?

Esomeprazole Magnesium contains Esomeprazole Magnesium, while Lansoprazole contains Lansoprazole — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.