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ACIPHEX vs PREVACID 24 HR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Rating

New
64/100

Pharmacy pays

~$5.10 /30

Type

RX
OTC

Active ingredient

RABEPRAZOLE SODIUM
LANSOPRAZOLE

Dosage forms

Tablet, delayed release
Capsule, delayed release

Drug class

Proton Pump Inhibitor
Proton Pump Inhibitor

Boxed warning

None
None

Half-life

about 1.5 hours (mean, ±1.0) in healthy adults — the label states the plasma elimination half-life is less than two hours

Treats

Duodenal Ulcer, Gastroesophageal Reflux, Heartburn
Duodenal Ulcer, Esophagitis, Gastroesophageal Reflux

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

What is the difference between Aciphex and Prevacid 24 Hr?

Aciphex contains Rabeprazole Sodium, while Prevacid 24 Hr contains Lansoprazole — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.