olanzapine
Olanzapine is an atypical antipsychotic used to treat Bipolar Disorder, Psychotic Disorders, Schizophrenia.
Atypical Antipsychotic · by Sun Pharm Inds Inc
Generic of Zyprexa
Key facts
- Active ingredient
- Olanzapine
- Drug class
- Atypical Antipsychotic
- Form
- Injectable, Tablet, Tablet, orally disintegrating
- Strength
- Olanzapine 10MG · Olanzapine 15MG · Olanzapine 20MG · Olanzapine 5MG
- Type
- Prescription (Rx)
- Brand or generic
- Generic
- May treat
- bipolar disorder, psychotic disorders, schizophrenia
- Manufacturer
- Sun Pharm Inds Inc
- Half-life
- about 21 to 54 hours (mean around 30 hours) (how long it stays in your system)
- What the pharmacy pays
- ~$4.13 for 30 — not your price
- FDA application
- ANDA090881
- Availability
- Discontinued (per FDA)
Storing Olanzapine, and how long it keeps
Quoted from this product’s own FDA label. Storage belongs to the product and its device, not to the drug in general — a pen and a tablet of the same medicine are kept completely differently.
- “Store olanzapine orally disintegrating tablets, USP at 20° to 25°C (68° to 77°F) [ see USP Controlled Room Temperature].”
- “Store olanzapine tablets at 20°C to 25°C (68°F to 77°F); excursions permitted from 15°C to 30°C (59°F to 86°F) [ see USP Controlled Room Temperature].”
- “Store olanzapine tablets at 20°C to 25°C (68°F to 77°F); excursions permitted from 15°C to 30°C (59°F to 86°F) [see USP Controlled Room Temperature].”
- “Store olanzapine tablets at controlled room temperature, 20° to 25°C (68° to 77°F) [see USP].”
- “Store Olanzapine for Injection vials (before reconstitution) at controlled room temperature, 20° to 25°C (68° to 77°F) [ see USP Controlled Room Temperature].”
How long does Olanzapine stay in your body?
The elimination half-life of olanzapine is about 21 to 54 hours (mean around 30 hours) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. The label gives the half-life as a population range: 21 to 54 hours (5th to 95th percentile, mean 30 hr) for oral olanzapine. The major circulating metabolites (10-N-glucuronide and 4'-N-desmethyl olanzapine) are explicitly described as lacking pharmacological activity, so there is no active metabolite that outlasts the parent to worry about. Half-life is longer in older adults: the mean elimination half-life was about 1.5 times greater in elderly (65+) than in younger subjects. Renal impairment: little effect (only ~7% excreted unchanged; not removed by dialysis; no dose adjustment). Hepatic impairment: a study in mild-to-moderate cirrhosis (Child-Pugh A/B) showed little effect on pharmacokinetics. Clearance is also ~30% lower in women and ~40% lower in nonsmokers, which lengthens half-life. This is the oral tablet; the long-acting olanzapine pamoate injection is a different formulation.
This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Olanzapine tablet — DailyMed label, Section 12.3 Pharmacokinetics.
Drug class
How this class works, per Atypical Antipsychotic Agents - StatPearls - NCBI Bookshelf.
May treat (source: NIH RxClass)
See how Olanzapine ranks — best-rated atypical antipsychotic for:
Dosage forms
Injectable, Tablet and Tablet, orally disintegrating
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Olanzapine treat?
- Olanzapine (Olanzapine) may be used to treat bipolar disorder, psychotic disorders, schizophrenia, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How does Olanzapine work?
- Olanzapine is a atypical antipsychotic. Atypical antipsychotics block dopamine D2 receptors and serotonin 5-HT2A receptors in the brain, rebalancing these signaling chemicals to reduce hallucinations, delusions, and mood symptoms in conditions like schizophrenia and bipolar disorder.
- How much does Olanzapine cost?
- Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $4.13 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
- Is there a coupon or discount for Olanzapine?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Olanzapine. To pay less, Olanzapine is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Olanzapine?
- Olanzapine is marketed by Sun Pharm Inds Inc. You can see Sun Pharm Inds Inc's full profile, rating, and other products on pharmaranks.
- Is Olanzapine a brand-name or generic drug?
- Olanzapine is a generic medication; its active ingredient is Olanzapine. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
- Is Olanzapine available over the counter?
- No. Olanzapine is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Olanzapine come in?
- Olanzapine is currently marketed as injectable, tablet and tablet, orally disintegrating, per the FDA's National Drug Code Directory.
- What class of drug is Olanzapine?
- Olanzapine is classified as atypical antipsychotic, per the FDA's Established Pharmacologic Class.
- Is Olanzapine FDA-registered?
- Olanzapine is on record with the U.S. FDA under application number ANDA090881. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
Reviews
No reviews yet. Be the first to write one.
People also viewed
aristada
Aripiprazole Lauroxil
aristada initio kit
Aripiprazole Lauroxil
asenapine maleate
Asenapine Maleate
geodon
Ziprasidone Hydrochloride
invega
Paliperidone
invega hafyera
Paliperidone Palmitate
Compare Olanzapine head-to-head
More atypical antipsychotic drugs
Guides for this medication
Browse medications A–Z
Research products from A to Z, compare independent ratings, and find alternatives.
olanzapine
New