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ASENAPINE MALEATE vs OLANZAPINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Possible drug interaction. ASENAPINE MALEATE and OLANZAPINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
New

Pharmacy pays

~$73.98 /30
~$4.13 /30

Type

RX
RX

Active ingredient

ASENAPINE MALEATE
OLANZAPINE

Dosage forms

Tablet
Injectable, Tablet, Tablet, orally disintegrating

Drug class

Atypical Antipsychotic
Atypical Antipsychotic

Boxed warning

Half-life

about 24 hours (terminal/elimination half-life)
about 21 to 54 hours (mean around 30 hours)

Treats

Bipolar Disorder, Schizophrenia
Bipolar Disorder, Psychotic Disorders, Schizophrenia

Frequently asked questions

Which is cheaper, Asenapine Maleate or Olanzapine?

Olanzapine costs pharmacies less to acquire — about $4.13 vs $73.98 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Asenapine Maleate and Olanzapine?

Asenapine Maleate contains Asenapine Maleate, while Olanzapine contains Olanzapine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.