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estraderm

Pharmaranks rates Estraderm 3.5/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Estraderm (Estradiol) is an estrogen used to treat Breast Neoplasms, Hypogonadism, Premature Menopause, Menorrhagia.

Estradiol · by Novartis

Available as a generic: Estradiol

70/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Estradiol
Drug class
Estrogen
Form
System
Strength
Estradiol 0.05MG/24HR · Estradiol 0.1MG/24HR
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Novartis
What the pharmacy pays
~$6.55 per gm — not your price
FDA application
NDA019081
Availability
Discontinued (per FDA)

Drug class

How this class works, per Estrogen - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

Dosage forms

System

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Estraderm treat?
Estraderm (Estradiol) may be used to treat breast neoplasms, hypogonadism, premature menopause, menorrhagia, prostatic neoplasms, primary ovarian insufficiency, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Estraderm work?
Estraderm is a estrogen. Estrogen is a sex hormone that enters cells and binds estrogen receptors; the hormone-receptor complex then moves into the nucleus and switches target genes on or off. Through this it thickens the uterine lining, helps protect bone, supports breast and vaginal tissue, and shapes cholesterol levels.
How is Estraderm rated?
pharmaranks gives Estraderm a composite score of 3.5 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
How much does Estraderm cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $6.55 per gm, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Estraderm?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Estraderm. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Estraderm?
Estraderm is marketed by Novartis. You can see Novartis's full profile, rating, and other products on pharmaranks.
Is Estraderm a brand-name or generic drug?
Estraderm is a brand-name product with the active ingredient Estradiol. Lower-cost generic equivalents containing Estradiol are available — ask your pharmacist.
Is Estraderm available over the counter?
No. Estraderm is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Estraderm come in?
Estraderm is currently marketed as system, per the FDA's National Drug Code Directory.
What class of drug is Estraderm?
Estraderm is classified as estrogen, per the FDA's Established Pharmacologic Class.
Is Estraderm FDA-registered?
Estraderm is on record with the U.S. FDA under application number NDA019081. You can verify this on its official FDA label.
Has Estraderm been recalled by the FDA?
Estraderm has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Estraderm safe?
There's no single safe-or-not verdict. pharmaranks gives Estraderm a recall-safety score of 70/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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estraderm

70/100