ELESTRIN vs ESTRADERM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Attribute	ELESTRIN	ESTRADERM
Rating	70/100	70/100
Pharmacy pays	$6.55 /g	$6.55 /g
Type	RX	RX
Active ingredient	ESTRADIOL	ESTRADIOL
Manufacturer	Viatris	Novartis
Dosage forms	Topical, metered	System
Drug class	Estrogen	Estrogen
Boxed warning	Boxed warning	None
Treats	Breast Neoplasms, Hypogonadism, Premature Menopause	Breast Neoplasms, Hypogonadism, Premature Menopause

elestrin estraderm

Rating

70/100

Pharmacy pays

$6.55 /g

Type

Active ingredient

ESTRADIOL

Manufacturer

Viatris

Novartis

Dosage forms

Topical, metered

System

Drug class

Estrogen

Boxed warning

None

Treats

Breast Neoplasms, Hypogonadism, Premature Menopause

Frequently asked questions

Which is better-rated, Elestrin or Estraderm?

Elestrin and Estraderm are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Elestrin or Estraderm?

Pharmacies pay about the same to acquire either one — roughly $6.55 per gm, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Elestrin and Estraderm?

Both Elestrin and Estraderm share the active ingredient Estradiol.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.