Best treatments for prostatic neoplasms
29 products may treat prostatic neoplasms, spanning FDA drug classes such as androgen receptor inhibitor, estrogen, 5-alpha reductase inhibitor. The current highest-rated option is firmagon. Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.
Quick answer: Of the 29 drugs we list for prostatic neoplasms, 17 are available as lower-cost generics, spanning classes such as androgen receptor inhibitor, estrogen, 5-alpha reductase inhibitor. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for prostatic neoplasms — so confirm the right choice with your prescriber.
Understanding prostatic neoplasms
Prostate cancer begins in the cells of the prostate, a gland in the male reproductive system that lies just below the bladder and in front of the rectum, surrounds part of the urethra, and makes fluid that is part of semen (NCI; MedlinePlus). In the United States, about one out of eight men will be diagnosed with prostate cancer, and it often grows very slowly (NCI; MedlinePlus). Early prostate cancer usually does not cause symptoms. When symptoms occur, they can include a weak, interrupted, or hard-to-start urine stream, frequent urination (especially at night), or trouble emptying the bladder; more advanced disease may cause blood in the urine or semen or persistent pain in the back, hips, or pelvis (NCI; MedlinePlus). Diagnosis may involve a digital rectal exam and a PSA blood test, but a biopsy is the only way to confirm prostate cancer; the biopsy also establishes the grade (Gleason score/Grade Group) (NCI; MedlinePlus). Findings are combined into a stage. Management ranges from watchful waiting or active surveillance to active treatment, guided by the cancer's characteristics and the person's health. This is general information, not medical advice.
First-line treatment
There is no single treatment that is best for everyone; in many cases no one option is clearly better than the others, and it can help to get more than one opinion, including from different types of specialists (ACS). Treatment selection depends on the stage of the cancer, the PSA level, the Gleason score/Grade Group, whether the cancer has spread, the person's age and overall health, life expectancy, and personal preferences about possible side effects (NCI; ACS). Because early prostate cancer often grows slowly, categories of standard options include watchful waiting or active surveillance, surgery (radical prostatectomy), radiation therapy, hormone therapy, chemotherapy, targeted therapy, and immunotherapy (NCI; ACS). The specific plan — including whether to treat immediately or monitor — is individualized for each patient and should be decided with a qualified oncology care team. This is general information, not medical advice.
Top-rated picks for prostatic neoplasms: 1. Firmagon · 2. Xtandi · 3. Casodex
| # | Drug | Rating | Type | Form | Class | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|---|
| 1 | 72/100 | Prescription | Kit | — | No data | — | View → | |
| 2 | 72/100 | Prescription | Tablet | Androgen Receptor Inhibitor | No data | — | View → | |
| 3 | 70/100 | Prescription | Tablet | Androgen Receptor Inhibitor | Generic | $12 | View → | |
| 4 | 70/100 | Prescription | Topical | Estrogen | Generic | $7 | View → | |
| 5 | 70/100 | Prescription | Spray/Inhaler | Estrogen | Generic | $7 | View → | |
| 6 | 70/100 | Prescription | Insert | Estrogen | Generic | $7 | View → | |
| 7 | 70/100 | Prescription | Kit | — | No data | — | View → | |
| 8 | 70/100 | Prescription | Tablet | 5-alpha Reductase Inhibitor | Generic | $2 | View → | |
| 9 | 70/100 | Prescription | Tablet | 5-alpha Reductase Inhibitor | Generic | $2 | View → | |
| 10 | 70/100 | Prescription | Insert | Estrogen | Generic | $7 | View → |
Narrow by drug class
Explore the class hubs: estrogen · 5-alpha reductase inhibitor · androgen receptor inhibitor · topoisomerase inhibitor
Full ranking · 29 treatments
firmagon
PrescriptionFDA-sourced
Firmagon (Degarelix Acetate) is a medication used to treat Prostatic Neoplasms.
Price varies
xtandi
PrescriptionFDA-sourced
Xtandi (Enzalutamide) is an androgen receptor inhibitor used to treat Prostatic Neoplasms.
Price varies
casodex
PrescriptionFDA-sourced
Casodex (Bicalutamide) is an androgen receptor inhibitor used to treat Prostatic Neoplasms.
Pharmacy pays
~$12.17 /30
elestrin
Boxed warningPrescriptionFDA-sourced
Elestrin (Estradiol) is an estrogen used to treat Breast Neoplasms, Hypogonadism, Premature Menopause, Menorrhagia.
Pharmacy pays
From ~$0.07· 8 forms
evamist
Boxed warningPrescriptionFDA-sourced
Evamist (Estradiol) is an estrogen used to treat Breast Neoplasms, Hypogonadism, Premature Menopause, Menorrhagia.
Pharmacy pays
From ~$0.07· 8 formsimvexxy
PrescriptionFDA-sourced
Imvexxy (Estradiol) is an estrogen used to treat Breast Neoplasms, Hypogonadism, Premature Menopause, Menorrhagia.
Pharmacy pays
From ~$0.07· 8 forms- Jevtana Kit
- Propecia
- Proscar
- Vagifem
- Enzalutamide
- Estradiol
- Nubeqa
- Vivelle-Dot
- Estring
- Minivelle
- Avopef
- Cerianna
- Climara
- Delestrogen
- Erleada
- Estrogel
- Etoposide
- Femring
- Finasteride
- Menostar
- Orgovyx
- Trelstar
- Zoladex
Frequently asked
- What treats prostatic neoplasms?
- Our catalog lists 29 products that may treat prostatic neoplasms, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is firmagon.
- What is the best-rated treatment for prostatic neoplasms?
- By our independent recall-safety rating — not an efficacy measure — firmagon ranks highest among the products we list for prostatic neoplasms. Always consult a professional.
- How are these treatments ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
- What types of drugs treat prostatic neoplasms?
- Treatments for prostatic neoplasms span FDA drug classes including androgen receptor inhibitor, estrogen, 5-alpha reductase inhibitor, topoisomerase inhibitor, gonadotropin releasing hormone receptor antagonist. Compare every option side by side, ranked by independent rating, above.
Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.
Sources
The clinical overview above is written from these authoritative public-health and medical-society sources, independently reviewed against each.