Skip to content
ppharmaranks
Menu

imvexxy

Pharmaranks rates Imvexxy 3.6/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Imvexxy (Estradiol) is an estrogen used to treat Breast Neoplasms, Hypogonadism, Premature Menopause, Menorrhagia.

Estradiol · by Mayne Pharma

Available as a generic: Estradiol

72/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Estradiol
Drug class
Estrogen
Form
Insert
Strength
Estradiol 0.004MG · Estradiol 0.01MG
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Mayne Pharma
What the pharmacy pays
~$6.42 per gm — not your price
FDA application
NDA208564

Drug class

How this class works, per Estrogen - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

Dosage forms

Insert

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Imvexxy treat?
Imvexxy (Estradiol) may be used to treat breast neoplasms, hypogonadism, premature menopause, menorrhagia, prostatic neoplasms, primary ovarian insufficiency, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Imvexxy work?
Imvexxy is a estrogen. Estrogen is a sex hormone that enters cells and binds estrogen receptors; the hormone-receptor complex then moves into the nucleus and switches target genes on or off. Through this it thickens the uterine lining, helps protect bone, supports breast and vaginal tissue, and shapes cholesterol levels.
How is Imvexxy rated?
pharmaranks gives Imvexxy a composite score of 3.6 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
How much does Imvexxy cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $6.42 per gm, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Imvexxy?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Imvexxy. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Imvexxy?
Imvexxy is marketed by Mayne Pharma. You can see Mayne Pharma's full profile, rating, and other products on pharmaranks.
Is Imvexxy a brand-name or generic drug?
Imvexxy is a brand-name product with the active ingredient Estradiol. Lower-cost generic equivalents containing Estradiol are available — ask your pharmacist.
Is Imvexxy available over the counter?
No. Imvexxy is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Imvexxy come in?
Imvexxy is currently marketed as insert, per the FDA's National Drug Code Directory.
What class of drug is Imvexxy?
Imvexxy is classified as estrogen, per the FDA's Established Pharmacologic Class.
Is Imvexxy FDA-registered?
Imvexxy is on record with the U.S. FDA under application number NDA208564. You can verify this on its official FDA label.
Has Imvexxy been recalled by the FDA?
Imvexxy has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Imvexxy safe?
There's no single safe-or-not verdict. pharmaranks gives Imvexxy a recall-safety score of 72/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

What people report to the FDA about ESTRADIOL

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 81,226 reports naming ESTRADIOL — the active ingredient in Imvexxy, and the FDA flagged 51% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • product adhesion issue8,308 reports
  • fatigue6,370 reports
  • headache5,420 reports
  • nausea5,319 reports
  • dyspnoea4,641 reports
  • rash4,525 reports
  • pruritus4,446 reports
  • arthralgia4,427 reports

Read these as a signal, not a rate. A report does not mean ESTRADIOL caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 25, 2026.

Reviews

No reviews yet. Be the first to write one.

Write a review

Reviews are user opinions, not medical advice. Consult a licensed professional.

People also viewed

Compare Imvexxy head-to-head

More estrogen drugs

Identify a pill by its imprint →Check a drug interaction →Drug recalls →

Browse medications A–Z

Research products from A to Z, compare independent ratings, and find alternatives.