avopef
Avopef (Etoposide) is a topoisomerase inhibitor used to treat Urinary Bladder Neoplasms, Brain Neoplasms, Lung Neoplasms, Mycosis Fungoides.
Etoposide · by Avyxa Holdings
Available as a generic: Etoposide
Key facts
- Active ingredient
- Etoposide
- Drug class
- Topoisomerase Inhibitor
- Form
- Injectable
- Strength
- Etoposide 100MG/5ML (20MG/ML) · Etoposide 500MG/25ML (20MG/ML)
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- Manufacturer
- Avyxa Holdings
- FDA application
- NDA220200
Drug class
How this class works, per Topoisomerase Inhibitors - LiverTox - NCBI Bookshelf.
May treat (source: NIH RxClass)
- urinary bladder neoplasms
- brain neoplasms
- lung neoplasms
- mycosis fungoides
- neuroblastoma
- prostatic neoplasms
See how Avopef ranks — best-rated topoisomerase inhibitor for:
Dosage forms
Injectable
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
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Frequently asked questions
- What does Avopef treat?
- Avopef (Etoposide) may be used to treat urinary bladder neoplasms, brain neoplasms, lung neoplasms, mycosis fungoides, neuroblastoma, prostatic neoplasms, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How does Avopef work?
- Avopef is a topoisomerase inhibitor. Topoisomerase inhibitors target enzymes that cells rely on to cut and rejoin their DNA during cell division. By trapping these enzymes after they cut the DNA but before they can reseal it, the drugs leave the DNA broken, which halts cell division and kills rapidly dividing cancer cells.
- Is there a coupon or discount for Avopef?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Avopef. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Avopef?
- Avopef is marketed by Avyxa Holdings. You can see Avyxa Holdings's full profile, rating, and other products on pharmaranks.
- Is Avopef a brand-name or generic drug?
- Avopef is a brand-name product with the active ingredient Etoposide. Lower-cost generic equivalents containing Etoposide are available — ask your pharmacist.
- Is Avopef available over the counter?
- No. Avopef is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Avopef come in?
- Avopef is currently marketed as injectable, per the FDA's National Drug Code Directory.
- What class of drug is Avopef?
- Avopef is classified as topoisomerase inhibitor, per the FDA's Established Pharmacologic Class.
- Is Avopef FDA-registered?
- Avopef is on record with the U.S. FDA under application number NDA220200. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about ETOPOSIDE
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 76,930 reports naming ETOPOSIDE — the active ingredient in Avopef, and the FDA flagged 97% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- febrile neutropenia8,167 reports
- neutropenia5,326 reports
- thrombocytopenia4,305 reports
- pyrexia3,691 reports
- anaemia3,492 reports
- sepsis3,165 reports
- pancytopenia2,926 reports
- nausea2,700 reports
Read these as a signal, not a rate. A report does not mean ETOPOSIDE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 25, 2026.
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