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xylocaine 4% preservative free

Pharmaranks rates Xylocaine 4% Preservative Free 3.4/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Xylocaine 4% Preservative Free (Lidocaine Hydrochloride) is an amide local anesthetic used to treat Burns, Esophageal Diseases, Mouth Diseases, Myocardial Infarction.

Lidocaine Hydrochloride · by Fresenius Kabi USA

Available as a generic: Lidocaine Hydrochloride Preservative Free

⚠ FDA reports a current shortage of the injection form — availability differs between suppliers — see drug shortages →
68/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Pharmacy acquisition cost fell 7% — $0.2619 → $0.2434 per ml (CMS NADAC)source

Verified againstopenFDANIH DailyMedRxClass
Lower-cost optionsSave up to 74%
This medication~$0.24
Cheapest in class · exparel~$0.06
See FDA-approved alternatives

Key facts

Active ingredient
Lidocaine Hydrochloride
Form
Injectable, Solution
Strength
Lidocaine Hydrochloride 4% · Lidocaine Hydrochloride 4% **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Fresenius Kabi USA
What the pharmacy pays
~$0.24 per ml — not your price
FDA application
NDA010417
Availability
Discontinued (per FDA)

Drug class

How this class works, per Topical, Local, and Regional Anesthesia and Anesthetics - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

See how Xylocaine 4% Preservative Free ranks — best-rated amide local anesthetic for:

Dosage forms

Injectable and Solution

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Xylocaine 4% Preservative Free treat?
Xylocaine 4% Preservative Free (Lidocaine Hydrochloride) may be used to treat burns, esophageal diseases, mouth diseases, myocardial infarction, pain, paroxysmal tachycardia, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Xylocaine 4% Preservative Free work?
Xylocaine 4% Preservative Free is a amide local anesthetic. Amide local anesthetics temporarily block the sodium channels that nerves use to fire, so the treated nerves can't send signals. This numbs pain in the area, and because the block reverses as the drug wears off, sensation returns afterward.
How is Xylocaine 4% Preservative Free rated?
pharmaranks gives Xylocaine 4% Preservative Free a composite score of 3.4 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
How much does Xylocaine 4% Preservative Free cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.24 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Exparel — about $0.06 on the same basis.
Is there a coupon or discount for Xylocaine 4% Preservative Free?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Xylocaine 4% Preservative Free. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Xylocaine 4% Preservative Free?
Xylocaine 4% Preservative Free is marketed by Fresenius Kabi USA. You can see Fresenius Kabi USA's full profile, rating, and other products on pharmaranks.
Is Xylocaine 4% Preservative Free a brand-name or generic drug?
Xylocaine 4% Preservative Free is a brand-name product with the active ingredient Lidocaine Hydrochloride. Lower-cost generic equivalents containing Lidocaine Hydrochloride are available — ask your pharmacist.
Is Xylocaine 4% Preservative Free available over the counter?
No. Xylocaine 4% Preservative Free is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Xylocaine 4% Preservative Free come in?
Xylocaine 4% Preservative Free is currently marketed as injectable and solution, per the FDA's National Drug Code Directory.
What class of drug is Xylocaine 4% Preservative Free?
Xylocaine 4% Preservative Free is classified as amide local anesthetic, antiarrhythmic, per the FDA's Established Pharmacologic Class.
Is Xylocaine 4% Preservative Free FDA-registered?
Xylocaine 4% Preservative Free is on record with the U.S. FDA under application number NDA010417. You can verify this on its official FDA label.
Has Xylocaine 4% Preservative Free been recalled by the FDA?
Xylocaine 4% Preservative Free has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Xylocaine 4% Preservative Free safe?
There's no single safe-or-not verdict. pharmaranks gives Xylocaine 4% Preservative Free a recall-safety score of 68/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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xylocaine 4% preservative free

68/100