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Best treatments for mouth diseases

6 products may treat mouth diseases, spanning FDA drug classes such as amide local anesthetic, antiarrhythmic. The current highest-rated option is lidocaine hydrochloride preservative free. Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.

Quick answer: Of the 6 drugs we list for mouth diseases, all are available as lower-cost generics, spanning classes such as amide local anesthetic, antiarrhythmic. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for mouth diseases — so confirm the right choice with your prescriber.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Top-rated picks for mouth diseases: 1. Lidocaine Hydrochloride Preservative Free · 2. Akten · 3. Bondlido

Top-rated treatments for mouth diseases, ranked by pharmaranks score
#DrugRatingPharmacy pays
172/100$0View →
270/100$0View →
3Not yet rated$0View →
4Not yet rated$0View →
5Not yet rated$0View →
6Not yet rated$0View →

Full ranking · 6 treatments

#1 of 15 in Amide Local Anesthetic

lidocaine hydrochloride preservative free

PrescriptionFDA-sourced

72/100

Lidocaine Hydrochloride Preservative Free (Lidocaine Hydrochloride) is an amide local anesthetic used to treat Burns, Esophageal Diseases, Mouth Diseases, Myocardial Infarction.

(10 data points)
amide local anestheticantiarrhythmicburns

Pharmacy pays

From ~$0.07· 8 forms Save up to 74% in class
View details →
THEA PHARMA logo
#2 of 15 in Amide Local Anesthetic

akten

PrescriptionFDA-sourced

70/100

Akten (Lidocaine Hydrochloride) is an amide local anesthetic used to treat Burns, Esophageal Diseases, Mouth Diseases, Myocardial Infarction.

(2 data points)
amide local anestheticantiarrhythmicburns

Pharmacy pays

From ~$0.07· 8 forms Save up to 74% in class
View details →

bondlido

PrescriptionFDA-sourced

New

Bondlido (Lidocaine) is an amide local anesthetic used to treat Burns, Esophageal Diseases, Mouth Diseases, Pain.

amide local anestheticantiarrhythmicburns

Pharmacy pays

From ~$0.07· 8 forms Save up to 74% in class
View details →

lidoderm

PrescriptionFDA-sourced

New

Lidoderm (Lidocaine) is an amide local anesthetic used to treat Burns, Esophageal Diseases, Mouth Diseases, Pain.

amide local anestheticantiarrhythmicburns

Pharmacy pays

From ~$0.07· 8 forms Save up to 74% in class
View details →

zingo

PrescriptionFDA-sourced

New

Zingo (Lidocaine Hydrochloride) is an amide local anesthetic used to treat Burns, Esophageal Diseases, Mouth Diseases, Myocardial Infarction.

amide local anestheticantiarrhythmicburns

Pharmacy pays

From ~$0.07· 8 forms Save up to 74% in class
View details →

ztlido

PrescriptionFDA-sourced

New

Ztlido (Lidocaine) is an amide local anesthetic used to treat Burns, Esophageal Diseases, Mouth Diseases, Pain.

amide local anestheticantiarrhythmicburns

Pharmacy pays

From ~$0.07· 8 forms Save up to 74% in class
View details →

Frequently asked

What treats mouth diseases?
Our catalog lists 6 products that may treat mouth diseases, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is lidocaine hydrochloride preservative free.
What is the best-rated treatment for mouth diseases?
By our independent recall-safety rating — not an efficacy measure — lidocaine hydrochloride preservative free ranks highest among the products we list for mouth diseases. Always consult a professional.
How are these treatments ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
What types of drugs treat mouth diseases?
Treatments for mouth diseases span FDA drug classes including amide local anesthetic, antiarrhythmic. Compare every option side by side, ranked by independent rating, above.

Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.