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Pharmaranks rates Lexapro 3.6/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Lexapro (Escitalopram Oxalate) is a serotonin reuptake inhibitor used to treat Major Depressive Disorder.

Escitalopram Oxalate · by Abbvie

Available as a generic: Escitalopram Oxalate

72/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Escitalopram Oxalate
Form
Tablet
Strength
Escitalopram Oxalate EQ 5MG BASE/5ML **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Abbvie
Half-life
about 27 to 32 hours (how long it stays in your system)
What the pharmacy pays
~$0.16 per ml — not your price
FDA application
NDA021365
Availability
Discontinued (per FDA)

How long does Escitalopram Oxalate stay in your body?

The elimination half-life of escitalopram oxalate is about 27 to 32 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the terminal (elimination) half-life of escitalopram itself; the drug's metabolites do not meaningfully add to its activity or duration. The half-life is longer in some people — about 50% longer in older adults and roughly doubled in those with reduced liver function.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: LEXAPRO (escitalopram oxalate) tablet — DailyMed label, Clinical Pharmacology/Pharmacokinetics.

Drug class

How this class works, per Selective Serotonin Reuptake Inhibitors - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

Dosage forms

Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Lexapro treat?
Lexapro (Escitalopram Oxalate) may be used to treat major depressive disorder, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Lexapro work?
Lexapro is a serotonin reuptake inhibitor. Selective serotonin reuptake inhibitors (SSRIs) block the transporter that pulls serotonin back into nerve cells, so more of this mood-related chemical stays in the gaps between neurons to keep signaling. They act mainly on serotonin, which tends to mean fewer side effects than older antidepressants.
How is Lexapro rated?
pharmaranks gives Lexapro a composite score of 3.6 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
How much does Lexapro cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.16 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Lexapro?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Lexapro. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Lexapro?
Lexapro is marketed by Abbvie. You can see Abbvie's full profile, rating, and other products on pharmaranks.
Is Lexapro a brand-name or generic drug?
Lexapro is a brand-name product with the active ingredient Escitalopram Oxalate. Lower-cost generic equivalents containing Escitalopram Oxalate are available — ask your pharmacist.
Is Lexapro available over the counter?
No. Lexapro is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Lexapro come in?
Lexapro is currently marketed as tablet, per the FDA's National Drug Code Directory.
What class of drug is Lexapro?
Lexapro is classified as serotonin reuptake inhibitor, per the FDA's Established Pharmacologic Class.
Is Lexapro FDA-registered?
Lexapro is on record with the U.S. FDA under application number NDA021365. You can verify this on its official FDA label.
Has Lexapro been recalled by the FDA?
Lexapro has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Lexapro safe?
There's no single safe-or-not verdict. pharmaranks gives Lexapro a recall-safety score of 72/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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