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Does Escitalopram (Lexapro) cause weight gain?

The honest answer from the FDA-approved label for Escitalopram (Lexapro)— what the trials actually reported, not the “every drug makes you gain weight” folklore.

By the pharmaranks editorial teamReviewed against the FDA drug label for Escitalopram sourcesUpdated Jul 21, 2026How we research

What the label reports

In controlled trials, patients treated with escitalopram did not differ from placebo-treated patients with regard to clinically important change in body weight. The label notes that decreased appetite and weight loss have been observed with SSRIs in children and adolescents, so weight and growth should be monitored in that group; and post-marketing reports list both increased and decreased weight. For adults, the label establishes no systematic weight effect.

Frequently asked questions

Does Escitalopram cause weight gain?

Not by the evidence. Escitalopram's FDA label does not report a systematic weight-gain effect (details above) — which matters, because "this drug makes you gain weight" is repeated online for almost every medication. Individual people can still see the scale move for other reasons (appetite returning as a condition improves, fluid, lifestyle), so track your own trend and raise it with your prescriber.

How much weight can Escitalopram cause?

The label reports what the trials found (above) and does not hand out a single number that applies to everyone — weight change depends on dose, duration, your starting point, and why you are taking the drug. If your weight is changing in a way that bothers you, that is a specific, fixable conversation with your prescriber, not a reason to quit abruptly.

Does the weight come off after stopping Escitalopram?

Often at least partly, when the drug's effect on appetite or metabolism was the cause — but that is individual, and some weight tracks lifestyle rather than the drug. Never stop a medication just to lose weight without talking to the prescriber first; for several of these drugs abrupt stopping has its own risks.

More guides for Escitalopram

Source

Escitalopram FDA Prescribing Information (DailyMed)

Other drugs: Amitriptyline · Amlodipine · Bupropion · Citalopram · Duloxetine · Fluconazole · Fluoxetine · Gabapentin · Ibuprofen · Levothyroxine · Metformin · Mirtazapine · Naproxen · Olanzapine · all drugs.

The weight information is what the drug’s FDA-approved label reports from its trials. This is general reference information, not medical advice, and weight change is individual — do not start or stop a medication to change your weight without your prescriber.