indocin

How long does Indomethacin stay in your body?

The elimination half-life of indomethacin is about 4.5 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the parent drug's mean elimination half-life; at ~4.5 hours most of a dose clears from the blood in roughly a day (about 5 half-lives). Indomethacin undergoes appreciable enterohepatic circulation (it is reabsorbed from the gut), which can prolong how long it lingers. It is broken down to desmethyl, desbenzoyl, and desmethyldesbenzoyl metabolites; the label does not describe these as active or longer-lasting than the parent. The label reports no half-life data in kidney or liver impairment because indomethacin's pharmacokinetics were not studied in those patients, though clearance may be slower when organ function is reduced.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: INDOMETHACIN capsule — FDA label (DailyMed), Clinical Pharmacology: Pharmacokinetics.

Frequently asked questions

What does Indocin treat?

Indocin (Indomethacin) may be used to treat rheumatoid arthritis, bursitis, patent ductus arteriosus, inflammation, osteoarthritis, pain, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.

How does Indocin work?

Indocin is a nonsteroidal anti-inflammatory drug. NSAIDs block cyclooxygenase (COX) enzymes that your body uses to make prostaglandins, the chemicals behind pain, swelling, and fever. Lowering prostaglandins eases pain and inflammation and brings down a high temperature.

How much does Indocin cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $4.06 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Indocin?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Indocin. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Indocin?

Indocin is marketed by Zyla Life Sciences. You can see Zyla Life Sciences's full profile, rating, and other products on pharmaranks.

Is Indocin a brand-name or generic drug?

Indocin is a brand-name product with the active ingredient Indomethacin. Lower-cost generic equivalents containing Indomethacin are available — ask your pharmacist.

Is Indocin available over the counter?

No. Indocin is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Indocin come in?

Indocin is currently marketed as suppository, per the FDA's National Drug Code Directory.

What class of drug is Indocin?

Indocin is classified as nonsteroidal anti-inflammatory drug, per the FDA's Established Pharmacologic Class.

Is Indocin FDA-registered?

Indocin is on record with the U.S. FDA under application number NDA017814. You can verify this on its official FDA label.

Has Indocin been recalled by the FDA?

Indocin has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.

Is Indocin safe?

There's no single safe-or-not verdict, and we don't yet have a composite recall-safety score for Indocin. Review its FDA-label side effects and warnings below, and always consult a licensed professional.