NSAIDs compared

Compare all 34 NSAIDs side by side, used for conditions such as arthritis, juvenile, arthritis, rheumatoid, bursitis. NSAIDs are the Nonsteroidal Anti-inflammatory Drug class. They share one FDA-defined mechanism but differ in approved uses, prescription status, brand-vs-generic options, price, and FDA recall-safety record — which our independent rating scores. The highest-rated is advil.

Top-rated nonsteroidal anti-inflammatory drug: 1. Advil · 2. Flector · 3. Junior Strength Advil

Nonsteroidal Anti-inflammatory Drug drugs compared side by side, with pharmaranks' FDA recall-safety rating
Drug	Generic	Form	Status	Used for	Safety ratingFDA recall-based	Pharmacy pays
Advil	Ibuprofen	Tablet	Over-the-counter	Arthritis, Juvenile, Arthritis, Rheumatoid	72/100	$0
Flector	Diclofenac Epolamine	System	Prescription	Arthritis, Juvenile, Arthritis, Rheumatoid	72/100	$146
Junior Strength Advil	Ibuprofen	Tablet	Over-the-counter	Arthritis, Juvenile, Arthritis, Rheumatoid	72/100	$0
Naproxen	—	Tablet	Prescription	Arthritis, Juvenile, Arthritis, Rheumatoid	72/100	$0
Voltaren Arthritis Pain	Diclofenac Sodium	Topical	Over-the-counter	Arthritis, Juvenile, Arthritis, Rheumatoid	72/100	$0
Advil Liqui-Gels	Ibuprofen	Capsule	Over-the-counter	Arthritis, Juvenile, Arthritis, Rheumatoid	70/100	$0
Advil Migraine Liqui-Gels	Ibuprofen	Capsule	Over-the-counter	Arthritis, Juvenile, Arthritis, Rheumatoid	70/100	$0
Midol Liquid Gels	Ibuprofen	Capsule	Over-the-counter	Arthritis, Juvenile, Arthritis, Rheumatoid	70/100	$0
Motrin Ib	Ibuprofen	Capsule	Over-the-counter	Arthritis, Juvenile, Arthritis, Rheumatoid	70/100	$0
Motrin Migraine Pain	Ibuprofen	Tablet	Prescription	Arthritis, Juvenile, Arthritis, Rheumatoid	70/100	$0
Nuprin	Ibuprofen	Tablet	Prescription	Arthritis, Juvenile, Arthritis, Rheumatoid	70/100	$0
Xifyrm	Meloxicam	Injectable	Prescription	Arthritis, Rheumatoid, Osteoarthritis	70/100	$1

The safety rating column is unique to pharmaranks — an independent 0–100 score from FDA regulatory recall data. Higher is safer. Not medical advice.

Best nonsteroidal anti-inflammatory drug by condition

for juvenile arthritis for rheumatoid arthritis for bursitis for dysmenorrhea for fever for gout

Full ranking · 34 drugs

Frequently asked questions

What is the Nonsteroidal Anti-inflammatory Drug drug class?

Nonsteroidal Anti-inflammatory Drug is an FDA Established Pharmacologic Class (EPC) — a group of drugs that share a mechanism of action. pharmaranks lists 34 Nonsteroidal Anti-inflammatory Drug products, each independently rated.

Are all Nonsteroidal Anti-inflammatory Drug drugs the same?

No. Nonsteroidal Anti-inflammatory Drug drugs share the same core mechanism — that is why they sit in one FDA class — but they differ in their approved uses, available forms, whether they are prescription or over-the-counter, brand-vs-generic options and price, and their FDA recall-safety record.

Is "NSAIDs" the same as the Nonsteroidal Anti-inflammatory Drug class?

Yes — "NSAIDs" is the everyday name for the Nonsteroidal Anti-inflammatory Drug drug class. This page compares the 34 NSAIDs pharmaranks rates, with our independent FDA recall-safety score for each.

What conditions do Nonsteroidal Anti-inflammatory Drug drugs treat?

Per NIH RxClass drug-classification data, Nonsteroidal Anti-inflammatory Drug drugs are used for conditions including arthritis, juvenile, arthritis, rheumatoid, bursitis, dysmenorrhea, fever, gout.

Which Nonsteroidal Anti-inflammatory Drug drug is best-rated?

By our independent rating, advil currently ranks highest among Nonsteroidal Anti-inflammatory Drug drugs. Ratings are based on FDA regulatory (recall-safety) data — always consult a professional.

Sources: the Nonsteroidal Anti-inflammatory Drug class definition and its member drugs come from the U.S. NLM RxClass (Established Pharmacologic Class); how the class works is summarized from Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) - StatPearls - NCBI Bookshelf. Ratings are pharmaranks’ independent FDA recall-safety analysis.