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aleve

Aleve (Naproxen Sodium) is a nonsteroidal anti-inflammatory drug used to treat Juvenile Arthritis, Rheumatoid Arthritis, Back Pain, Bursitis.

Naproxen Sodium · by Bayer Pharms

Available as a generic: Naproxen Sodium

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
$0.06 /mL
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Lower-cost optionsSave up to 34%
This medication~$0.06
Cheapest in class · advil~$0.04
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Key facts

Active ingredient
Naproxen Sodium
Form
Capsule, Tablet
Strength
Naproxen Sodium 220MG
Type
Over-the-counter (OTC)
Brand or generic
Brand-name
Manufacturer
Bayer Pharms
Half-life
about 12 to 17 hours (how long it stays in your system)
What the pharmacy pays
~$0.06 per ml — not your price
FDA application
NDA020204

What is Aleve?

From the FDA label:Uses temporarily relieves minor aches and pains due to: minor pain of arthritis muscular aches backache menstrual cramps headache toothache the common cold temporarily reduces fever

How to use

Aleve is sold in more than one form (Capsule and Tablet), and each is dosed differently. The instructions below come from the FDA label for application NDA020204 — follow the label that came with the product you were actually prescribed.

Directions do not take more than directed the smallest effective dose should be used drink a full glass of water with each dose Adults and children 12 years and older take 1 tablet every 8 to 12 hours while symptoms last for the first dose you may take 2 tablets within the first hour do not exceed 2 tablets in any 8- to 12-hour period do not exceed 3 tablets in a 24-hour period Children under 12 years ask a doctor

How long does Naproxen Sodium stay in your body?

The elimination half-life of naproxen sodium is about 12 to 17 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is naproxen's elimination (terminal) half-life in healthy adults; its metabolites have shorter half-lives, so there is no longer-acting active metabolite to account for. The half-life is prolonged in severe renal impairment, and above 500 mg/day the drug shows nonlinear (dose-dependent) kinetics because plasma protein binding becomes saturated.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: NAPROXEN tablet, delayed release — DailyMed (FDA label).

Drug class

How this class works, per Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

See how Aleve ranks — best-rated nonsteroidal anti-inflammatory drug for:

Dosage forms

Capsule and Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Aleve treat?
Aleve (Naproxen Sodium) may be used to treat juvenile arthritis, rheumatoid arthritis, back pain, bursitis, common cold, dysmenorrhea, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Aleve work?
Aleve is a nonsteroidal anti-inflammatory drug. NSAIDs block cyclooxygenase (COX) enzymes that your body uses to make prostaglandins, the chemicals behind pain, swelling, and fever. Lowering prostaglandins eases pain and inflammation and brings down a high temperature.
How much does Aleve cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.06 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Advil — about $0.04 on the same basis.
Is there a coupon or discount for Aleve?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Aleve. To pay less, look for a store-brand version with the same active ingredient (Naproxen Sodium), which is typically cheaper, and compare unit prices. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Aleve?
Aleve is marketed by Bayer Pharms. You can see Bayer Pharms's full profile, rating, and other products on pharmaranks.
Is Aleve a brand-name or generic drug?
Aleve is a brand-name product with the active ingredient Naproxen Sodium. Lower-cost generic equivalents containing Naproxen Sodium are available — ask your pharmacist.
Is Aleve available over the counter?
Yes. Aleve is an over-the-counter (OTC) product — you can buy it without a prescription. Follow the label directions and ask a pharmacist if you're unsure whether it's right for you.
What forms does Aleve come in?
Aleve is currently marketed as capsule and tablet, per the FDA's National Drug Code Directory.
What class of drug is Aleve?
Aleve is classified as nonsteroidal anti-inflammatory drug, per the FDA's Established Pharmacologic Class.
Is Aleve FDA-registered?
Aleve is on record with the U.S. FDA under application number NDA020204. You can verify this on its official FDA label.

Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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