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Best treatments for back pain

6 products may treat back pain, spanning FDA drug classes such as nonsteroidal anti-inflammatory drug. The current highest-rated option is naproxen. Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.

Quick answer: Of the 6 drugs we list for back pain, all are available as lower-cost generics, spanning classes such as nonsteroidal anti-inflammatory drug. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for back pain — so confirm the right choice with your prescriber.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate
Treatments we list for back pain
#DrugRatingPharmacy pays
172/100$0View →
2Not yet rated$0View →
3Not yet rated$0View →
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Full ranking · 6 treatments

#1 of 30 in Nonsteroidal Anti-inflammatory Drug

naproxen

Boxed warning

PrescriptionFDA-sourced

72/100

Naproxen is a nonsteroidal anti-inflammatory drug used to treat Juvenile Arthritis, Rheumatoid Arthritis, Back Pain, Bursitis.

(10 data points)
nonsteroidal anti-inflammatory drugarthritis, juvenilearthritis, rheumatoid

Pharmacy pays

From ~$0.05· 8 forms Save up to 34% in class
View details →

aleve

Over-the-counterFDA-sourced

New

Aleve (Naproxen Sodium) is a nonsteroidal anti-inflammatory drug used to treat Juvenile Arthritis, Rheumatoid Arthritis, Back Pain, Bursitis.

nonsteroidal anti-inflammatory drugarthritis, juvenilearthritis, rheumatoid

Pharmacy pays

From ~$0.05· 8 forms Save up to 34% in class
View details →

ec-naprosyn

Boxed warning

PrescriptionFDA-sourced

New

Ec-Naprosyn (Naproxen) is a nonsteroidal anti-inflammatory drug used to treat Juvenile Arthritis, Rheumatoid Arthritis, Back Pain, Bursitis.

nonsteroidal anti-inflammatory drugarthritis, juvenilearthritis, rheumatoid

Pharmacy pays

From ~$0.05· 8 forms Save up to 34% in class
View details →

naprelan

Boxed warning

PrescriptionFDA-sourced

New

Naprelan (Naproxen Sodium) is a nonsteroidal anti-inflammatory drug used to treat Juvenile Arthritis, Rheumatoid Arthritis, Back Pain, Bursitis.

nonsteroidal anti-inflammatory drugarthritis, juvenilearthritis, rheumatoid

Pharmacy pays

From ~$0.05· 8 forms Save up to 34% in class
View details →

naprosyn

PrescriptionFDA-sourced

New

Naprosyn (Naproxen) is a nonsteroidal anti-inflammatory drug used to treat Juvenile Arthritis, Rheumatoid Arthritis, Back Pain, Bursitis.

nonsteroidal anti-inflammatory drugarthritis, juvenilearthritis, rheumatoid

Pharmacy pays

From ~$0.05· 8 forms Save up to 34% in class
View details →

naproxen sodium

Over-the-counterFDA-sourced

New

Naproxen Sodium is a nonsteroidal anti-inflammatory drug used to treat Juvenile Arthritis, Rheumatoid Arthritis, Back Pain, Bursitis.

nonsteroidal anti-inflammatory drugarthritis, juvenilearthritis, rheumatoid

Pharmacy pays

From ~$0.05· 8 forms Save up to 34% in class
View details →

Frequently asked

What treats back pain?
Our catalog lists 6 products that may treat back pain, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is naproxen.
What is the best-rated treatment for back pain?
By our independent recall-safety rating — not an efficacy measure — naproxen ranks highest among the products we list for back pain. Always consult a professional.
How are these treatments ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
What types of drugs treat back pain?
Treatments for back pain span FDA drug classes including nonsteroidal anti-inflammatory drug. Compare every option side by side, ranked by independent rating, above.

Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.