inderal

How long does Propranolol Hydrochloride stay in your body?

The elimination half-life of propranolol hydrochloride is about 3 to 6 hours (plasma half-life, immediate-release, in healthy adults) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. Label figure is for immediate-release propranolol; extended-release products differ. Propranolol has an active metabolite, 4-hydroxypropranolol, formed after oral dosing; the label notes it is pharmacologically active but does not state a half-life for it, so no metabolite half-life is reported here. Half-life lengthens in the populations the label names: in older adults it is prolonged (about 11 hours vs. about 5 hours in young subjects), and in hepatic impairment (cirrhosis) it rises to about 11 hours vs. about 4 hours in controls, with roughly 3-fold higher unbound levels. In chronic renal failure the label reports a shorter (reduced) plasma half-life, yet peak and total plasma levels are 3 to 4 times higher, so a shorter number does not mean faster overall clearance. CYP2D6 poor vs. extensive metabolizer status did not change elimination half-life.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Propranolol Hydrochloride tablets — DailyMed label, Clinical Pharmacology / Pharmacokinetics.

Frequently asked questions

What does Inderal treat?

Inderal (Propranolol Hydrochloride) may be used to treat angina pectoris, esophageal and gastric varices, heart failure, hypertension, myocardial infarction, pheochromocytoma, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.

How does Inderal work?

Inderal is a beta-adrenergic blocker. Beta-blockers block adrenaline (epinephrine) and noradrenaline from acting on beta-adrenergic receptors, mainly in the heart. This slows the heart rate, reduces how forcefully the heart contracts, and lowers blood pressure, easing the workload on the heart.

How much does Inderal cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $2.49 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Atenolol — about $0.76 on the same basis.

Is there a coupon or discount for Inderal?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Inderal. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Inderal?

Inderal is marketed by Wyeth Ayerst. You can see Wyeth Ayerst's full profile, rating, and other products on pharmaranks.

Is Inderal a brand-name or generic drug?

Inderal is a brand-name product with the active ingredient Propranolol Hydrochloride. Lower-cost generic equivalents containing Propranolol Hydrochloride are available — ask your pharmacist.

Is Inderal available over the counter?

No. Inderal is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Inderal come in?

Inderal is currently marketed as tablet, per the FDA's National Drug Code Directory.

What class of drug is Inderal?

Inderal is classified as beta-adrenergic blocker, per the FDA's Established Pharmacologic Class.

Is Inderal FDA-registered?

Inderal is on record with the U.S. FDA under application number NDA019536. You can verify this on its official FDA label.