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propranolol hydrochloride

Propranolol Hydrochloride is a beta-adrenergic blocker used to treat Angina Pectoris, Esophageal and Gastric Varices, Heart Failure, Hypertension.

Beta-Adrenergic Blocker · by Chartwell Rx

Generic of Inderal La

⚠ FDA reports a current shortage of the injection form — availability differs between suppliers — see drug shortages →
Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
Lower-cost optionsSave up to 70%
This medication~$2.49/30
Cheapest in class · atenolol~$0.76/30
See FDA-approved alternatives

Key facts

Active ingredient
Propranolol Hydrochloride
Form
Injectable, Tablet
Strength
Propranolol Hydrochloride 60MG
Type
Prescription (Rx)
Brand or generic
Generic
Manufacturer
Chartwell Rx
Half-life
about 3 to 6 hours (plasma half-life, immediate-release, in healthy adults) (how long it stays in your system)
What the pharmacy pays
~$2.49 for 30 — not your price
FDA application
ANDA070666
Availability
Discontinued (per FDA)

How long does Propranolol Hydrochloride stay in your body?

The elimination half-life of propranolol hydrochloride is about 3 to 6 hours (plasma half-life, immediate-release, in healthy adults) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. Label figure is for immediate-release propranolol; extended-release products differ. Propranolol has an active metabolite, 4-hydroxypropranolol, formed after oral dosing; the label notes it is pharmacologically active but does not state a half-life for it, so no metabolite half-life is reported here. Half-life lengthens in the populations the label names: in older adults it is prolonged (about 11 hours vs. about 5 hours in young subjects), and in hepatic impairment (cirrhosis) it rises to about 11 hours vs. about 4 hours in controls, with roughly 3-fold higher unbound levels. In chronic renal failure the label reports a shorter (reduced) plasma half-life, yet peak and total plasma levels are 3 to 4 times higher, so a shorter number does not mean faster overall clearance. CYP2D6 poor vs. extensive metabolizer status did not change elimination half-life.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Propranolol Hydrochloride tablets — DailyMed label, Clinical Pharmacology / Pharmacokinetics.

Drug class

How this class works, per Beta Blockers — StatPearls, NCBI Bookshelf (NIH).

May treat (source: NIH RxClass)

See how Propranolol Hydrochloride ranks — best-rated beta-adrenergic blocker for:

Dosage forms

Injectable and Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Propranolol Hydrochloride treat?
Propranolol Hydrochloride (Propranolol Hydrochloride) may be used to treat angina pectoris, esophageal and gastric varices, heart failure, hypertension, myocardial infarction, pheochromocytoma, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Propranolol Hydrochloride work?
Propranolol Hydrochloride is a beta-adrenergic blocker. Beta-blockers block adrenaline (epinephrine) and noradrenaline from acting on beta-adrenergic receptors, mainly in the heart. This slows the heart rate, reduces how forcefully the heart contracts, and lowers blood pressure, easing the workload on the heart.
How much does Propranolol Hydrochloride cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $2.49 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Atenolol — about $0.76 on the same basis.
Is there a coupon or discount for Propranolol Hydrochloride?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Propranolol Hydrochloride. To pay less, Propranolol Hydrochloride is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Propranolol Hydrochloride?
Propranolol Hydrochloride is marketed by Chartwell Rx. You can see Chartwell Rx's full profile, rating, and other products on pharmaranks.
Is Propranolol Hydrochloride a brand-name or generic drug?
Propranolol Hydrochloride is a generic medication; its active ingredient is Propranolol Hydrochloride. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
Is Propranolol Hydrochloride available over the counter?
No. Propranolol Hydrochloride is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Propranolol Hydrochloride come in?
Propranolol Hydrochloride is currently marketed as injectable and tablet, per the FDA's National Drug Code Directory.
What class of drug is Propranolol Hydrochloride?
Propranolol Hydrochloride is classified as beta-adrenergic blocker, per the FDA's Established Pharmacologic Class.
Is Propranolol Hydrochloride FDA-registered?
Propranolol Hydrochloride is on record with the U.S. FDA under application number ANDA070666. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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