imodium multi-symptom relief
Pharmaranks rates Imodium Multi-Symptom Relief 3.5/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Imodium Multi-Symptom Relief is a combination medicine containing Loperamide Hydrochloride and Simethicone.
Loperamide Hydrochloride and Simethicone · by Kenvue Brands
Available as a generic: Loperamide Hydrochloride and Simethicone
Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →
Key facts
- Active ingredient
- Loperamide Hydrochloride and Simethicone
- Form
- Tablet
- Strength
- Loperamide Hydrochloride 2MG; Simethicone 125MG
- Type
- Over-the-counter (OTC)
- Brand or generic
- Brand-name
- Manufacturer
- Kenvue Brands
- Half-life
- about 10.8 hours (range 9.1 to 14.4 hours) (how long it stays in your system)
- What the pharmacy pays
- ~$0.05 per ml — not your price
- FDA application
- NDA021140
What is Imodium Multi-Symptom Relief?
From the FDA label:Uses relieves symptoms of diarrhea plus bloating, pressure and cramps, commonly referred to as gas
How to use
Directions drink plenty of clear fluids to help prevent dehydration caused by diarrhea take only on an empty stomach (1 hour before or 2 hours after a meal) take with a full (8 oz.) glass of water find right dose on chart below. If possible, use weight to dose; otherwise, use age. adults and children 12 years and over 2 caplets after the first loose stool; 1 caplet after each subsequent loose stool; but no more than 4 caplets in 24 hours children 9-11 years (60-95 lbs) 1 caplet after the first loose stool; ½ caplet after each subsequent loose stool; but no more than 3 caplets in 24 hours children 6-8 years (48-59 lbs) 1 caplet after the first loose stool; ½ caplet after each subsequent loose stool; but no more than 2 caplets in 24 hours children 2-5 years (34 to 47 lbs) ask a doctor children under 2 years (up to 33 lbs) do not use
Warnings
Important safety information
Allergy alert Do not use if you have ever had a rash or other allergic reaction to loperamide HCl Heart alert Taking more than directed can cause serious heart problems or death Do not use if you have bloody or black stool if you have difficulty swallowing Ask a doctor before use if you have fever mucus in the stool a history of liver disease a history of abnormal heart rhythm Ask a doctor or pharmacist before use if you are taking a prescription drug. Loperamide may interact with certain prescription drugs. When using this product tiredness, drowsiness or dizziness may occur. Be careful when driving or operating machinery. Stop use and ask a doctor if symptoms get worse diarrhea lasts for more than 2 days you get abdominal swelling or bulging. These may be signs of a serious condition. you have difficulty swallowing the caplet If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)
How long does Loperamide Hydrochloride and Simethicone stay in your body?
The elimination half-life of loperamide hydrochloride and simethicone is about 10.8 hours (range 9.1 to 14.4 hours) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. Per the FDA label, the apparent elimination half-life of loperamide is 10.8 hours (range 9.1–14.4 hours), so most of a dose clears in roughly 2–3 days. Loperamide is metabolized in the liver (mainly CYP2C8 and CYP3A4) via N-demethylation; the label does not characterize the N-demethyl metabolite's half-life, so no metabolite-specific clearance number is given. People with liver impairment clear it more slowly (reduced first-pass metabolism — use with caution); the label reports no pharmacokinetic data in kidney impairment, and no major disposition differences in elderly patients.
This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: IMODIUM (loperamide hydrochloride) capsule — DailyMed FDA label.
Dosage forms
Tablet
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- How is Imodium Multi-Symptom Relief rated?
- pharmaranks gives Imodium Multi-Symptom Relief a composite score of 3.5 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
- How much does Imodium Multi-Symptom Relief cost?
- Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.05 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Advil Pm — about $0.04 on the same basis.
- Is there a coupon or discount for Imodium Multi-Symptom Relief?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Imodium Multi-Symptom Relief. To pay less, look for a store-brand version with the same active ingredient (Loperamide Hydrochloride and Simethicone), which is typically cheaper, and compare unit prices. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Imodium Multi-Symptom Relief?
- Imodium Multi-Symptom Relief is marketed by Kenvue Brands. You can see Kenvue Brands's full profile, rating, and other products on pharmaranks.
- Is Imodium Multi-Symptom Relief a brand-name or generic drug?
- Imodium Multi-Symptom Relief is a brand-name product with the active ingredient Loperamide Hydrochloride and Simethicone. Lower-cost generic equivalents containing Loperamide Hydrochloride and Simethicone are available — ask your pharmacist.
- Is Imodium Multi-Symptom Relief available over the counter?
- Yes. Imodium Multi-Symptom Relief is an over-the-counter (OTC) product — you can buy it without a prescription. Follow the label directions and ask a pharmacist if you're unsure whether it's right for you.
- What forms does Imodium Multi-Symptom Relief come in?
- Imodium Multi-Symptom Relief is currently marketed as tablet, per the FDA's National Drug Code Directory.
- Is Imodium Multi-Symptom Relief FDA-registered?
- Imodium Multi-Symptom Relief is on record with the U.S. FDA under application number NDA021140. You can verify this on its official FDA label.
- Has Imodium Multi-Symptom Relief been recalled by the FDA?
- Imodium Multi-Symptom Relief has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
- Is Imodium Multi-Symptom Relief safe?
- There's no single safe-or-not verdict. pharmaranks gives Imodium Multi-Symptom Relief a recall-safety score of 70/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.
Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
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imodium multi-symptom relief
70/100