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ABREVA vs IMODIUM MULTI-SYMPTOM RELIEF

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Rating

72/100
70/100

Pharmacy pays

$6.64 /g
$0.05 /mL

Type

OTC
OTC

Active ingredient

DOCOSANOL
LOPERAMIDE HYDROCHLORIDE AND SIMETHICONE

Dosage forms

Topical
Tablet

Drug class

Boxed warning

None
None

Half-life

about 10.8 hours (range 9.1 to 14.4 hours)

Treats

Blister

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

Which is better-rated, Abreva or Imodium Multi-Symptom Relief?

By our independent rating, Abreva scores higher — 3.6 vs 3.5 out of 5 for Imodium Multi-Symptom Relief. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Abreva and Imodium Multi-Symptom Relief?

Abreva contains Docosanol, while Imodium Multi-Symptom Relief contains Loperamide Hydrochloride and Simethicone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.