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hydroxyzine pamoate

Pharmaranks rates Hydroxyzine Pamoate 3.5/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Hydroxyzine Pamoate is an antihistamine used to treat Anxiety Disorders, Nausea, Pruritus, Substance Withdrawal Syndrome.

Antihistamine · by Watson Labs

70/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Hydroxyzine Pamoate
Drug class
Antihistamine
Form
Capsule
Strength
Hydroxyzine Pamoate EQ 50MG Hydrochloride
Type
Prescription (Rx)
Brand or generic
Generic
Manufacturer
Watson Labs
Half-life
about 14 to 20 hours in healthy adults (two reported mean values: 20.0 ± 4.1 hours and 14.0 hours) (how long it stays in your system)
FDA application
ANDA086695
Availability
Discontinued (per FDA)

How long does Hydroxyzine Pamoate stay in your body?

The elimination half-life of hydroxyzine pamoate is about 14 to 20 hours in healthy adults (two reported mean values: 20.0 ± 4.1 hours and 14.0 hours) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the parent drug's elimination half-life. It varies a lot by age — averaging about 29 hours in older adults and about 7 hours in children. Hydroxyzine is broken down into an active metabolite, cetirizine (itself an antihistamine), which is cleared by the kidneys and can build up when kidney function is impaired.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Hydroxyzine Hydrochloride 25 mg Film-coated Tablets — Summary of Product Characteristics (SmPC), section 5.2 Pharmacokinetic properties.

Drug class

May treat (source: NIH RxClass)

Dosage forms

Capsule

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Hydroxyzine Pamoate treat?
Hydroxyzine Pamoate (Hydroxyzine Pamoate) may be used to treat anxiety disorders, nausea, pruritus, substance withdrawal syndrome, vomiting, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How is Hydroxyzine Pamoate rated?
pharmaranks gives Hydroxyzine Pamoate a composite score of 3.5 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
Is there a coupon or discount for Hydroxyzine Pamoate?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Hydroxyzine Pamoate. To pay less, Hydroxyzine Pamoate is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Hydroxyzine Pamoate?
Hydroxyzine Pamoate is marketed by Watson Labs. You can see Watson Labs's full profile, rating, and other products on pharmaranks.
Is Hydroxyzine Pamoate a brand-name or generic drug?
Hydroxyzine Pamoate is a generic medication; its active ingredient is Hydroxyzine Pamoate. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
Is Hydroxyzine Pamoate available over the counter?
No. Hydroxyzine Pamoate is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Hydroxyzine Pamoate come in?
Hydroxyzine Pamoate is currently marketed as capsule, per the FDA's National Drug Code Directory.
What class of drug is Hydroxyzine Pamoate?
Hydroxyzine Pamoate is classified as antihistamine, per the FDA's Established Pharmacologic Class.
Is Hydroxyzine Pamoate FDA-registered?
Hydroxyzine Pamoate is on record with the U.S. FDA under application number ANDA086695. You can verify this on its official FDA label.
Has Hydroxyzine Pamoate been recalled by the FDA?
Hydroxyzine Pamoate has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Hydroxyzine Pamoate safe?
There's no single safe-or-not verdict. pharmaranks gives Hydroxyzine Pamoate a recall-safety score of 70/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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hydroxyzine pamoate

70/100