Best treatments for pruritus
11 products may treat pruritus, spanning FDA drug classes such as corticosteroid, tricyclic antidepressant, ileal bile acid transporter inhibitor. The current highest-rated option is asmanex hfa. Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.
Quick answer: Of the 11 drugs we list for pruritus, 8 are available as lower-cost generics, spanning classes such as corticosteroid, tricyclic antidepressant, ileal bile acid transporter inhibitor. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for pruritus — so confirm the right choice with your prescriber.
Top-rated picks for pruritus: 1. Asmanex Hfa · 2. Asmanex Twisthaler · 3. Fluocinonide Emulsified Base
| # | Drug | Rating | Type | Form | Class | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|---|
| 1 | 70/100 | Prescription | Spray/Inhaler | Corticosteroid | Generic | $0 | View → | |
| 2 | 70/100 | Prescription | Spray/Inhaler | Corticosteroid | Generic | $0 | View → | |
| 3 | 70/100 | Prescription | Topical | Corticosteroid | Generic | $0 | View → | |
| 4 | 66/100 | Prescription | Topical | Tricyclic Antidepressant | Generic | $5 | View → | |
| 5 | 64/100 | Over-the-counter | Spray/Inhaler | Corticosteroid | Generic | $0 | View → | |
| 6 | Not yet rated | Prescription | Capsule | Ileal Bile Acid Transporter Inhibitor | No data | — | View → | |
| 7 | Not yet rated | Prescription | Injectable | Antihistamine | Generic | $0 | View → | |
| 8 | Not yet rated | Prescription | Injectable | — | No data | — | View → | |
| 9 | Not yet rated | Prescription | Tablet | Ileal Bile Acid Transporter Inhibitor | No data | — | View → | |
| 10 | Not yet rated | Prescription | Implant | Corticosteroid | Generic | $0 | View → |
Narrow by drug class
Explore the class hubs: corticosteroid · ileal bile acid transporter inhibitor
Full ranking · 11 treatments
asmanex hfa
PrescriptionFDA-sourced
Asmanex Hfa (Mometasone Furoate) is a corticosteroid used to treat Facial Dermatoses, Foot Dermatoses, Hand Dermatoses, Inflammation.
Pharmacy pays
From ~$0.26· 4 forms Save up to 65% in classasmanex twisthaler
PrescriptionFDA-sourced
Asmanex Twisthaler (Mometasone Furoate) is a corticosteroid used to treat Facial Dermatoses, Foot Dermatoses, Hand Dermatoses, Inflammation.
Pharmacy pays
From ~$0.26· 4 forms Save up to 65% in classfluocinonide emulsified base
PrescriptionFDA-sourced
Fluocinonide Emulsified Base (Fluocinonide) is a corticosteroid used to treat Facial Dermatoses, Foot Dermatoses, Hand Dermatoses, Inflammation.
Pharmacy pays
From ~$0.21· 5 forms Save up to 53% in classzonalon
PrescriptionFDA-sourced
Zonalon (Doxepin Hydrochloride) is a tricyclic antidepressant used to treat Anxiety Disorders, Depressive Disorder, Atopic Dermatitis, Pain.
Pharmacy pays
From ~$2.38/30· 8 forms Save up to 47% in class
nasonex 24hr allergy
Over-the-counterFDA-sourced
Nasonex 24hr Allergy (Mometasone Furoate) is a corticosteroid used to treat Facial Dermatoses, Foot Dermatoses, Hand Dermatoses, Inflammation.
Pharmacy pays
From ~$0.26· 4 forms Save up to 65% in class
bylvay
PrescriptionFDA-sourced
Bylvay (Odevixibat) is an ileal bile acid transporter inhibitor used to treat Pruritus.
Price varies
Frequently asked
- What treats pruritus?
- Our catalog lists 11 products that may treat pruritus, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is asmanex hfa.
- What is the best-rated treatment for pruritus?
- By our independent recall-safety rating — not an efficacy measure — asmanex hfa ranks highest among the products we list for pruritus. Always consult a professional.
- How are these treatments ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
- What types of drugs treat pruritus?
- Treatments for pruritus span FDA drug classes including corticosteroid, tricyclic antidepressant, ileal bile acid transporter inhibitor, antihistamine. Compare every option side by side, ranked by independent rating, above.
Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.