Best treatments for nausea
8 products may treat nausea, spanning FDA drug classes such as phenothiazine, antihistamine. The current highest-rated option is procomp. Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.
Quick answer: Of the 8 drugs we list for nausea, 6 are available as lower-cost generics, spanning classes such as phenothiazine, antihistamine. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for nausea — so confirm the right choice with your prescriber.
Top-rated picks for nausea: 1. Procomp · 2. Promethegan · 3. Perphenazine
| # | Drug | Rating | Type | Form | Class | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|---|
| 1 | 70/100 | Prescription | Tablet | Phenothiazine | Generic | $5 | View → | |
| 2 | 70/100 | Prescription | Suppository | Phenothiazine | Generic | $2 | View → | |
| 3 | 68/100 | Prescription | Tablet | Phenothiazine | Generic | $6 | View → | |
| 4 | Not yet rated | Prescription | Injectable | Antihistamine | Generic | $0 | View → | |
| 5 | Not yet rated | Prescription | Capsule | — | No data | — | View → | |
| 6 | Not yet rated | Prescription | Injectable | Phenothiazine | No data | — | View → | |
| 7 | Not yet rated | Prescription | Tablet | Phenothiazine | Generic | $5 | View → | |
| 8 | Not yet rated | Prescription | Syrup | Phenothiazine | Generic | $2 | View → |
Full ranking · 8 treatments
procomp
PrescriptionFDA-sourced
Procomp (Prochlorperazine Maleate) is a phenothiazine used to treat Anxiety Disorders, Dementia, Nausea, Psychotic Disorders.
Pharmacy pays
From ~$3.48/30· 3 forms Save up to 71% in classpromethegan
Boxed warningPrescriptionFDA-sourced
Promethegan (Promethazine Hydrochloride) is a phenothiazine used to treat Anaphylaxis, Allergic Conjunctivitis, Motion Sickness, Nausea.
Pharmacy pays
From ~$1.41/30· 8 forms
perphenazine
Boxed warningPrescriptionFDA-sourced
Perphenazine is a phenothiazine used to treat Tourette Syndrome, Huntington Disease, Nausea, Psychotic Disorders.
Pharmacy pays
From ~$4.95/30· 4 forms Save up to 73% in classhydroxyzine hydrochloride
PrescriptionFDA-sourced
Hydroxyzine Hydrochloride is an antihistamine used to treat Anxiety Disorders, Nausea, Pruritus, Substance Withdrawal Syndrome.
Pharmacy pays
From ~$0.03· 5 formsmarinol
PrescriptionFDA-sourced
Marinol (Dronabinol) is a medication used to treat Anorexia, Nausea, Vomiting.
Price varies
prochlorperazine edisylate
Boxed warningPrescriptionFDA-sourced
Prochlorperazine Edisylate is a phenothiazine used to treat Anxiety Disorders, Dementia, Nausea, Psychotic Disorders.
Frequently asked
- What treats nausea?
- Our catalog lists 8 products that may treat nausea, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is procomp.
- What is the best-rated treatment for nausea?
- By our independent recall-safety rating — not an efficacy measure — procomp ranks highest among the products we list for nausea. Always consult a professional.
- How are these treatments ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
- What types of drugs treat nausea?
- Treatments for nausea span FDA drug classes including phenothiazine, antihistamine. Compare every option side by side, ranked by independent rating, above.
Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.