Best Phenothiazine for nausea
Top-rated pick: Procomp — pharmaranks score 70/100, the highest of the 6 Phenothiazine drugs used for nausea, ranked by our independent FDA recall-safety score. Compare them with all treatments for nausea or the full Phenothiazine class. Not medical advice — always consult a professional.
Quick answer: Of the 6 phenothiazine drugs we rate for nausea, 5 are available as lower-cost generics, and most are tablet. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for nausea; the right choice depends on your situation, so confirm it with your prescriber.
Top phenothiazine for nausea: 1. Procomp · 2. Promethegan · 3. Perphenazine
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | 70/100 | Prescription | Tablet | Generic | $5 | View → | |
| 2 | 70/100 | Prescription | Suppository | Generic | $2 | View → | |
| 3 | 68/100 | Prescription | Tablet | Generic | $6 | View → | |
| 4 | Not yet rated | Prescription | Injectable | No data | — | View → | |
| 5 | Not yet rated | Prescription | Tablet | Generic | $5 | View → | |
| 6 | Not yet rated | Prescription | Syrup | Generic | $2 | View → |
Full ranking · 6 drugs
procomp
PrescriptionFDA-sourced
Procomp (Prochlorperazine Maleate) is a phenothiazine used to treat Anxiety Disorders, Dementia, Nausea, Psychotic Disorders.
Pharmacy pays
From ~$3.48/30· 3 forms Save up to 71% in classpromethegan
Boxed warningPrescriptionFDA-sourced
Promethegan (Promethazine Hydrochloride) is a phenothiazine used to treat Anaphylaxis, Allergic Conjunctivitis, Motion Sickness, Nausea.
Pharmacy pays
From ~$1.41/30· 8 forms
perphenazine
Boxed warningPrescriptionFDA-sourced
Perphenazine is a phenothiazine used to treat Tourette Syndrome, Huntington Disease, Nausea, Psychotic Disorders.
Pharmacy pays
From ~$4.95/30· 4 forms Save up to 73% in classprochlorperazine edisylate
Boxed warningPrescriptionFDA-sourced
Prochlorperazine Edisylate is a phenothiazine used to treat Anxiety Disorders, Dementia, Nausea, Psychotic Disorders.
prochlorperazine maleate
Boxed warningPrescriptionFDA-sourced
Prochlorperazine Maleate is a phenothiazine used to treat Anxiety Disorders, Dementia, Nausea, Psychotic Disorders.
Pharmacy pays
From ~$3.48/30· 3 forms Save up to 71% in classpromethazine plain
Boxed warningPrescriptionFDA-sourced
Promethazine Plain (Promethazine Hydrochloride) is a phenothiazine used to treat Anaphylaxis, Allergic Conjunctivitis, Motion Sickness, Nausea.
Pharmacy pays
From ~$1.41/30· 8 formsFrequently asked
- What is the best phenothiazine for nausea?
- By our independent recall-safety rating — not an efficacy measure — procomp ranks highest among Phenothiazine drugs used for nausea. Always consult a professional.
- Which phenothiazine drugs treat nausea?
- pharmaranks lists 6 Phenothiazine products used for nausea, per NIH RxClass drug-classification data — each independently rated and ranked above.
- How are these ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.