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dimenhydrinate

Pharmaranks rates Dimenhydrinate 3.6/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Dimenhydrinate is a histamine-1 receptor antagonist used to treat Motion Sickness, Nausea, Vertigo, Vomiting.

Histamine-1 Receptor Antagonist · by Watson Labs

72/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Dimenhydrinate
Form
Injectable, Tablet
Strength
Dimenhydrinate 50MG/ML
Type
Prescription (Rx)
Brand or generic
Generic
Manufacturer
Watson Labs
FDA application
ANDA083531
Availability
Discontinued (per FDA)

Drug class

How this class works, per Antihistamines - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

Dosage forms

Injectable and Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Dimenhydrinate treat?
Dimenhydrinate (Dimenhydrinate) may be used to treat motion sickness, nausea, vertigo, vomiting, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Dimenhydrinate work?
Dimenhydrinate is a histamine-1 receptor antagonist. H1 antihistamines work by blocking histamine, the chemical released during an allergic reaction, from attaching to H1 receptors. This prevents the sneezing, itching, runny nose, watery eyes, and hives that histamine would otherwise trigger.
How is Dimenhydrinate rated?
pharmaranks gives Dimenhydrinate a composite score of 3.6 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
Is there a coupon or discount for Dimenhydrinate?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Dimenhydrinate. To pay less, Dimenhydrinate is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Dimenhydrinate?
Dimenhydrinate is marketed by Watson Labs. You can see Watson Labs's full profile, rating, and other products on pharmaranks.
Is Dimenhydrinate a brand-name or generic drug?
Dimenhydrinate is a generic medication; its active ingredient is Dimenhydrinate. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
Is Dimenhydrinate available over the counter?
No. Dimenhydrinate is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Dimenhydrinate come in?
Dimenhydrinate is currently marketed as injectable and tablet, per the FDA's National Drug Code Directory.
What class of drug is Dimenhydrinate?
Dimenhydrinate is classified as histamine-1 receptor antagonist, per the FDA's Established Pharmacologic Class.
Is Dimenhydrinate FDA-registered?
Dimenhydrinate is on record with the U.S. FDA under application number ANDA083531. You can verify this on its official FDA label.
Has Dimenhydrinate been recalled by the FDA?
Dimenhydrinate has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Dimenhydrinate safe?
There's no single safe-or-not verdict. pharmaranks gives Dimenhydrinate a recall-safety score of 72/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

What people report to the FDA about Dimenhydrinate

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 5,545 reports naming Dimenhydrinate, and the FDA flagged 98% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • febrile neutropenia816 reports
  • nausea701 reports
  • vomiting474 reports
  • fatigue459 reports
  • pyrexia435 reports
  • inappropriate schedule of product administration355 reports
  • dizziness340 reports
  • dyspnoea338 reports

Read these as a signal, not a rate. A report does not mean Dimenhydrinate caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 25, 2026.

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dimenhydrinate

72/100