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busulfex

Busulfex (Busulfan) is an alkylating drug used to treat Polycythemia Vera, Bcr-Abl Positive Chronic Myelogenous Leukemia, Primary Myelofibrosis.

Busulfan · by Otsuka

Available as a generic: Busulfan

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Busulfan
Drug class
Alkylating Drug
Form
Injectable
Strength
Busulfan 6MG/ML
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Otsuka
FDA application
NDA020954

Drug class

How this class works, per Cyclophosphamide — StatPearls, NCBI Bookshelf (NIH).

May treat (source: NIH RxClass)

See how Busulfex ranks — best-rated alkylating drug for:

Dosage forms

Injectable

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Busulfex treat?
Busulfex (Busulfan) may be used to treat polycythemia vera, bcr-abl positive chronic myelogenous leukemia, primary myelofibrosis, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Busulfex work?
Busulfex is a alkylating drug. Alkylating chemotherapy drugs attach chemical groups to a cell's DNA, forming cross-links that lock the two DNA strands together. This damage stops the cell from copying its DNA and dividing, which triggers it to die; because they are not limited to one phase of the cell cycle, they can act on cells whether or not they are actively dividing.
Is there a coupon or discount for Busulfex?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Busulfex. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Busulfex?
Busulfex is marketed by Otsuka. You can see Otsuka's full profile, rating, and other products on pharmaranks.
Is Busulfex a brand-name or generic drug?
Busulfex is a brand-name product with the active ingredient Busulfan. Lower-cost generic equivalents containing Busulfan are available — ask your pharmacist.
Is Busulfex available over the counter?
No. Busulfex is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Busulfex come in?
Busulfex is currently marketed as injectable, per the FDA's National Drug Code Directory.
What class of drug is Busulfex?
Busulfex is classified as alkylating drug, per the FDA's Established Pharmacologic Class.
Is Busulfex FDA-registered?
Busulfex is on record with the U.S. FDA under application number NDA020954. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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