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busulfan

Pharmaranks rates Busulfan 3.6/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Busulfan is an alkylating drug used to treat Polycythemia Vera, Bcr-Abl Positive Chronic Myelogenous Leukemia, Primary Myelofibrosis.

Alkylating Drug · by Actavis

Generic of Busulfex

72/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Busulfan
Drug class
Alkylating Drug
Form
Injectable, Solution
Strength
Busulfan 6MG/ML
Type
Prescription (Rx)
Brand or generic
Generic
Manufacturer
Actavis
FDA application
ANDA205139
Availability
Discontinued (per FDA)

Drug class

How this class works, per Cyclophosphamide — StatPearls, NCBI Bookshelf (NIH).

May treat (source: NIH RxClass)

See how Busulfan ranks — best-rated alkylating drug for:

Dosage forms

Injectable and Solution

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Busulfan treat?
Busulfan (Busulfan) may be used to treat polycythemia vera, bcr-abl positive chronic myelogenous leukemia, primary myelofibrosis, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Busulfan work?
Busulfan is a alkylating drug. Alkylating chemotherapy drugs attach chemical groups to a cell's DNA, forming cross-links that lock the two DNA strands together. This damage stops the cell from copying its DNA and dividing, which triggers it to die; because they are not limited to one phase of the cell cycle, they can act on cells whether or not they are actively dividing.
How is Busulfan rated?
pharmaranks gives Busulfan a composite score of 3.6 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
Is there a coupon or discount for Busulfan?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Busulfan. To pay less, Busulfan is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Busulfan?
Busulfan is marketed by Actavis. You can see Actavis's full profile, rating, and other products on pharmaranks.
Is Busulfan a brand-name or generic drug?
Busulfan is a generic medication; its active ingredient is Busulfan. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
Is Busulfan available over the counter?
No. Busulfan is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Busulfan come in?
Busulfan is currently marketed as injectable and solution, per the FDA's National Drug Code Directory.
What class of drug is Busulfan?
Busulfan is classified as alkylating drug, per the FDA's Established Pharmacologic Class.
Is Busulfan FDA-registered?
Busulfan is on record with the U.S. FDA under application number ANDA205139. You can verify this on its official FDA label.
Has Busulfan been recalled by the FDA?
Busulfan has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Busulfan safe?
There's no single safe-or-not verdict. pharmaranks gives Busulfan a recall-safety score of 72/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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busulfan

72/100