Alkylating Drug drugs compared
Compare all 19 Alkylating Drug drugs side by side, used for conditions such as leukemia, lymphoid, lymphoma, non-hodgkin, brain neoplasms. They share one FDA-defined mechanism but differ in approved uses, prescription status, brand-vs-generic options, price, and FDA recall-safety record — which our independent rating scores. The highest-rated is bendeka.
Top-rated alkylating drug: 1. Bendeka · 2. Gleostine · 3. Gliadel
| Drug | Generic | Form | Status | Used for | Safety ratingFDA recall-based | Pharmacy pays |
|---|---|---|---|---|---|---|
| Bendeka | Bendamustine Hydrochloride | Injectable | Prescription | Leukemia, Lymphoid, Lymphoma, Non-Hodgkin | 70/100 | — |
| Gleostine | Lomustine | Capsule | Prescription | Brain Neoplasms, Colonic Neoplasms | 70/100 | — |
| Gliadel | Carmustine | Wafer | Prescription | Brain Neoplasms, Carcinoma | 70/100 | — |
| Vivimusta | Bendamustine Hydrochloride | Injectable | Prescription | Leukemia, Lymphoid, Lymphoma, Non-Hodgkin | 70/100 | — |
| Evdi | Trabectedin | Injectable | Prescription | Leiomyosarcoma, Liposarcoma | 66/100 | — |
| Ivra | Melphalan Hydrochloride | Injectable | Prescription | Breast Neoplasms, Multiple Myeloma | 66/100 | — |
| Bicnu | Carmustine | Kit | Prescription | Brain Neoplasms, Carcinoma | Not yet rated | — |
| Busulfex | Busulfan | Injectable | Prescription | Polycythemia Vera, Leukemia, Myelogenous, Chronic, Bcr-Abl Positive | Not yet rated | — |
| Evomela | Melphalan Hydrochloride | Injectable | Prescription | Breast Neoplasms, Multiple Myeloma | Not yet rated | — |
| Hepzato | Melphalan Hydrochloride | Kit | Prescription | Breast Neoplasms, Multiple Myeloma | Not yet rated | — |
| Lomustine | — | Capsule | Prescription | Brain Neoplasms, Colonic Neoplasms | Not yet rated | — |
| Melphalan Hydrochloride | — | Kit | Prescription | Breast Neoplasms, Multiple Myeloma | Not yet rated | — |
The safety rating column is unique to pharmaranks — an independent 0–100 score from FDA regulatory recall data. Higher is safer. Not medical advice.
Best alkylating drug by condition
Full ranking · 19 drugs
- 170/100
bendeka
Bendamustine Hydrochloride
- 270/100
gleostine
Lomustine
- 370/100
gliadel
Carmustine
- 470/100
vivimusta
Bendamustine Hydrochloride
- 566/100
evdi
Trabectedin
- 666/100
ivra
Melphalan Hydrochloride
- 7New
bicnu
Carmustine
- 8New
busulfex
Busulfan
- 9New
evomela
Melphalan Hydrochloride
- 10New
hepzato
Melphalan Hydrochloride
- 11New
lomustine
Lomustine
- 12New
melphalan hydrochloride
Melphalan Hydrochloride
- 13New
mitomycin
Mitomycin
- 14New
mitosol
Mitomycin
- 15New
myleran
Busulfan
- 16New
temozolomide
Temozolomide
- 17New
treanda
Bendamustine Hydrochloride
- 18New
yondelis
Trabectedin
- 19New
zusduri
Mitomycin
Frequently asked questions
What is the Alkylating Drug drug class?
Alkylating Drug is an FDA Established Pharmacologic Class (EPC) — a group of drugs that share a mechanism of action. pharmaranks lists 19 Alkylating Drug products, each independently rated.
Are all Alkylating Drug drugs the same?
No. Alkylating Drug drugs share the same core mechanism — that is why they sit in one FDA class — but they differ in their approved uses, available forms, whether they are prescription or over-the-counter, brand-vs-generic options and price, and their FDA recall-safety record.
What conditions do Alkylating Drug drugs treat?
Per NIH RxClass drug-classification data, Alkylating Drug drugs are used for conditions including leukemia, lymphoid, lymphoma, non-hodgkin, brain neoplasms, colonic neoplasms, hodgkin disease, kidney neoplasms.
Which Alkylating Drug drug is best-rated?
By our independent rating, bendeka currently ranks highest among Alkylating Drug drugs. Ratings are based on FDA regulatory (recall-safety) data — always consult a professional.
Sources: the Alkylating Drug class definition and its member drugs come from the U.S. NLM RxClass (Established Pharmacologic Class); how the class works is summarized from Cyclophosphamide — StatPearls, NCBI Bookshelf (NIH). Ratings are pharmaranks’ independent FDA recall-safety analysis.