evomela
Evomela (Melphalan Hydrochloride) is an alkylating drug used to treat Breast Neoplasms, Multiple Myeloma, Neuroblastoma, Ovarian Neoplasms.
Melphalan Hydrochloride · by Acrotech Biopharma
Available as a generic: Melphalan Hydrochloride
Key facts
- Active ingredient
- Melphalan Hydrochloride
- Drug class
- Alkylating Drug
- Form
- Injectable
- Strength
- Melphalan Hydrochloride EQ 50MG BASE/VIAL
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- May treat
- breast neoplasms, multiple myeloma, neuroblastoma
- Manufacturer
- Acrotech Biopharma
- FDA application
- NDA207155
Drug class
How this class works, per Cyclophosphamide — StatPearls, NCBI Bookshelf (NIH).
May treat (source: NIH RxClass)
See how Evomela ranks — best-rated alkylating drug for:
Dosage forms
Injectable
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Evomela treat?
- Evomela (Melphalan Hydrochloride) may be used to treat breast neoplasms, multiple myeloma, neuroblastoma, ovarian neoplasms, rhabdomyosarcoma, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How does Evomela work?
- Evomela is a alkylating drug. Alkylating chemotherapy drugs attach chemical groups to a cell's DNA, forming cross-links that lock the two DNA strands together. This damage stops the cell from copying its DNA and dividing, which triggers it to die; because they are not limited to one phase of the cell cycle, they can act on cells whether or not they are actively dividing.
- Is there a coupon or discount for Evomela?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Evomela. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Evomela?
- Evomela is marketed by Acrotech Biopharma. You can see Acrotech Biopharma's full profile, rating, and other products on pharmaranks.
- Is Evomela a brand-name or generic drug?
- Evomela is a brand-name product with the active ingredient Melphalan Hydrochloride. Lower-cost generic equivalents containing Melphalan Hydrochloride are available — ask your pharmacist.
- Is Evomela available over the counter?
- No. Evomela is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Evomela come in?
- Evomela is currently marketed as injectable, per the FDA's National Drug Code Directory.
- What class of drug is Evomela?
- Evomela is classified as alkylating drug, per the FDA's Established Pharmacologic Class.
- Is Evomela FDA-registered?
- Evomela is on record with the U.S. FDA under application number NDA207155. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about MELPHALAN HYDROCHLORIDE
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 2,529 reports naming MELPHALAN HYDROCHLORIDE — the active ingredient in Evomela, and the FDA flagged 97% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- pyrexia141 reports
- mucosal inflammation137 reports
- neutropenia122 reports
- febrile neutropenia116 reports
- diarrhoea111 reports
- pneumonia107 reports
- thrombocytopenia107 reports
- sepsis106 reports
Read these as a signal, not a rate. A report does not mean MELPHALAN HYDROCHLORIDE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 25, 2026.
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