Skip to content
ppharmaranks
Menu
Apotex logo

alkeran

Pharmaranks rates Alkeran 3.3/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Alkeran (Melphalan Hydrochloride) is an alkylating drug used to treat Breast Neoplasms, Multiple Myeloma, Neuroblastoma, Ovarian Neoplasms.

Melphalan Hydrochloride · by Apotex

Available as a generic: Melphalan Hydrochloride

66/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Melphalan Hydrochloride
Drug class
Alkylating Drug
Form
Tablet, Injectable
Strength
Melphalan Hydrochloride EQ 50MG BASE/VIAL **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Apotex
FDA application
NDA020207
Availability
Discontinued (per FDA)

Drug class

How this class works, per Cyclophosphamide — StatPearls, NCBI Bookshelf (NIH).

May treat (source: NIH RxClass)

See how Alkeran ranks — best-rated alkylating drug for:

Dosage forms

Tablet and Injectable

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Alkeran treat?
Alkeran (Melphalan Hydrochloride) may be used to treat breast neoplasms, multiple myeloma, neuroblastoma, ovarian neoplasms, rhabdomyosarcoma, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Alkeran work?
Alkeran is a alkylating drug. Alkylating chemotherapy drugs attach chemical groups to a cell's DNA, forming cross-links that lock the two DNA strands together. This damage stops the cell from copying its DNA and dividing, which triggers it to die; because they are not limited to one phase of the cell cycle, they can act on cells whether or not they are actively dividing.
How is Alkeran rated?
pharmaranks gives Alkeran a composite score of 3.3 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
Is there a coupon or discount for Alkeran?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Alkeran. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Alkeran?
Alkeran is marketed by Apotex. You can see Apotex's full profile, rating, and other products on pharmaranks.
Is Alkeran a brand-name or generic drug?
Alkeran is a brand-name product with the active ingredient Melphalan Hydrochloride. Lower-cost generic equivalents containing Melphalan Hydrochloride are available — ask your pharmacist.
Is Alkeran available over the counter?
No. Alkeran is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Alkeran come in?
Alkeran is currently marketed as tablet and injectable, per the FDA's National Drug Code Directory.
What class of drug is Alkeran?
Alkeran is classified as alkylating drug, per the FDA's Established Pharmacologic Class.
Is Alkeran FDA-registered?
Alkeran is on record with the U.S. FDA under application number NDA020207. You can verify this on its official FDA label.
Has Alkeran been recalled by the FDA?
Alkeran has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Alkeran safe?
There's no single safe-or-not verdict. pharmaranks gives Alkeran a recall-safety score of 66/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

Reviews

No reviews yet. Be the first to write one.

Write a review

Reviews are user opinions, not medical advice. Consult a licensed professional.

People also viewed

Compare Alkeran head-to-head

More alkylating drug drugs

Identify a pill by its imprint →Check a drug interaction →Drug recalls →

Browse medications A–Z

Research products from A to Z, compare independent ratings, and find alternatives.