ALKERAN vs GLEOSTINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. ALKERAN and GLEOSTINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ALKERAN	GLEOSTINE
Rating	66/100	70/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	MELPHALAN HYDROCHLORIDE	LOMUSTINE
Manufacturer	Apotex	Azurity
Dosage forms	Tablet, Injectable	Capsule
Drug class	Alkylating Drug	Alkylating Drug
Boxed warning	None	Boxed warning
Half-life	—	about 16 to 48 hours — but note this is the half-life of lomustine's metabolites, not the parent drug
Treats	Breast Neoplasms, Multiple Myeloma, Neuroblastoma	Brain Neoplasms, Colonic Neoplasms, Hodgkin Disease

alkeran gleostine

Rating

66/100

70/100

Pharmacy pays

—

Type

Active ingredient

MELPHALAN HYDROCHLORIDE

LOMUSTINE

Manufacturer

Apotex

Azurity

Dosage forms

Tablet, Injectable

Capsule

Drug class

Alkylating Drug

Boxed warning

None

Boxed warning

Half-life

—

about 16 to 48 hours — but note this is the half-life of lomustine's metabolites, not the parent drug

Treats

Breast Neoplasms, Multiple Myeloma, Neuroblastoma

Brain Neoplasms, Colonic Neoplasms, Hodgkin Disease

Frequently asked questions

Which is better-rated, Alkeran or Gleostine?

By our independent rating, Gleostine scores higher — 3.5 vs 3.3 out of 5 for Alkeran. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Alkeran and Gleostine?

Alkeran contains Melphalan Hydrochloride, while Gleostine contains Lomustine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.