Best Sulfonylurea for diabetes mellitus, type 2
Top-rated pick: Diabeta — pharmaranks score 70/100, the highest of the 5 Sulfonylurea drugs used for diabetes mellitus, type 2, ranked by our independent FDA recall-safety score. Compare them with all treatments for diabetes mellitus, type 2 or the full Sulfonylurea class. Not medical advice — always consult a professional.
Quick answer: Of the 5 sulfonylurea drugs we rate for diabetes mellitus, type 2, all are available as lower-cost generics, and most are tablet. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for diabetes mellitus, type 2; the right choice depends on your situation, so confirm it with your prescriber.
Other drug classes for diabetes mellitus, type 2
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Top sulfonylurea for diabetes mellitus, type 2: 1. Diabeta · 2. Glyburide · 3. Glipizide
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | 70/100 | Prescription | Tablet | Generic | $2 | View → | |
| 2 | 70/100 | Prescription | Tablet | Generic | $2 | View → | |
| 3 | 66/100 | Prescription | Tablet | Generic | $1 | View → | |
| 4 | 64/100 | Prescription | Tablet | Generic | $1 | View → | |
| 5 | Not yet rated | Prescription | Tablet | Generic | $1 | View → |
Full ranking · 5 drugs
diabeta
PrescriptionFDA-sourced
Diabeta (Glyburide) is a sulfonylurea used to treat Type 2 Diabetes Mellitus.
Pharmacy pays
From ~$1.70/30· 3 forms Save up to 49% in classglyburide
PrescriptionFDA-sourced
Glyburide is a sulfonylurea used to treat Type 2 Diabetes Mellitus.
Pharmacy pays
From ~$1.70/30· 3 forms Save up to 49% in class
glipizide
PrescriptionFDA-sourced
Glipizide is a sulfonylurea used to treat Type 2 Diabetes Mellitus.
Pharmacy pays
From ~$1.07/30· 6 forms Save up to 29% in class
glucotrol xl
PrescriptionFDA-sourced
Glucotrol XL (Glipizide) is a sulfonylurea used to treat Type 2 Diabetes Mellitus.
Pharmacy pays
From ~$1.07/30· 6 forms Save up to 29% in classglimepiride
PrescriptionFDA-sourced
Glimepiride is a sulfonylurea used to treat Type 2 Diabetes Mellitus.
Pharmacy pays
From ~$0.70/30· 3 formsFrequently asked
- What is the best sulfonylurea for diabetes mellitus, type 2?
- By our independent recall-safety rating — not an efficacy measure — diabeta ranks highest among Sulfonylurea drugs used for diabetes mellitus, type 2. Always consult a professional.
- Which sulfonylurea drugs treat diabetes mellitus, type 2?
- pharmaranks lists 5 Sulfonylurea products used for diabetes mellitus, type 2, per NIH RxClass drug-classification data — each independently rated and ranked above.
- How are these ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.