Which sodium-glucose cotransporter 2 inhibitor drugs treat diabetes mellitus, type 2?

pharmaranks lists 2 Sodium-Glucose Cotransporter 2 Inhibitor products used for diabetes mellitus, type 2, per NIH RxClass drug-classification data — each independently rated and ranked above.

How are these ranked?

By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.

Best Sodium-Glucose Cotransporter 2 Inhibitor for diabetes mellitus, type 2

Top-rated pick: Invokana — pharmaranks score 70/100, the highest of the 2 Sodium-Glucose Cotransporter 2 Inhibitor drugs used for diabetes mellitus, type 2, ranked by our independent FDA recall-safety score. Compare them with all treatments for diabetes mellitus, type 2 or the full Sodium-Glucose Cotransporter 2 Inhibitor class. Not medical advice — always consult a professional.

Quick answer: Of the 2 sodium-glucose cotransporter 2 inhibitor drugs we rate for diabetes mellitus, type 2, 1 is available as lower-cost generics, and most are tablet. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for diabetes mellitus, type 2; the right choice depends on your situation, so confirm it with your prescriber.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

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Top sodium-glucose cotransporter 2 inhibitor for diabetes mellitus, type 2: 1. Invokana · 2. Farxiga

Best-rated Sodium-Glucose Cotransporter 2 Inhibitor for diabetes mellitus, type 2, ranked by pharmaranks score
#	Drug	Rating	Type	Form	Generic?	Pharmacy pays
1	Invokana	70/100	Prescription	Tablet	No data	—	View →
2	Farxiga	Not yet rated	Prescription	Tablet	Generic	$6	View →

Full ranking · 2 drugs

invokana

PrescriptionFDA-sourced

70/100

Invokana (Canagliflozin) is a sodium-glucose cotransporter 2 inhibitor used to treat Type 2 Diabetes Mellitus.

(2 data points)

sodium-glucose cotransporter 2 inhibitordiabetes mellitus, type 2

Available online

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farxiga

PrescriptionFDA-sourced

New

Farxiga (Dapagliflozin) is a sodium-glucose cotransporter 2 inhibitor used to treat Type 2 Diabetes Mellitus.

sodium-glucose cotransporter 2 inhibitordiabetes mellitus, type 2

Pharmacy pays

From ~$5.54/30· 2 forms

View details →

Frequently asked

What is the best sodium-glucose cotransporter 2 inhibitor for diabetes mellitus, type 2?: By our independent recall-safety rating — not an efficacy measure — invokana ranks highest among Sodium-Glucose Cotransporter 2 Inhibitor drugs used for diabetes mellitus, type 2. Always consult a professional.
Which sodium-glucose cotransporter 2 inhibitor drugs treat diabetes mellitus, type 2?: pharmaranks lists 2 Sodium-Glucose Cotransporter 2 Inhibitor products used for diabetes mellitus, type 2, per NIH RxClass drug-classification data — each independently rated and ranked above.
How are these ranked?: By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.