Best GLP-1 Receptor Agonist for diabetes mellitus, type 2
Top-rated pick: Ozempic — pharmaranks score 70/100, the highest of the 9 GLP-1 Receptor Agonist drugs used for diabetes mellitus, type 2, ranked by our independent FDA recall-safety score. Compare them with all treatments for diabetes mellitus, type 2 or the full GLP-1 Receptor Agonist class. Not medical advice — always consult a professional.
Quick answer: Of the 9 GLP-1 receptor agonist drugs we rate for diabetes mellitus, type 2, 1 is available as lower-cost generics, and most are injectable. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for diabetes mellitus, type 2; the right choice depends on your situation, so confirm it with your prescriber.
How GLP-1 receptor agonist work
GLP-1 receptor agonists mimic the gut hormone GLP-1: they prompt the pancreas to release insulin when blood sugar is high, curb the release of glucagon, and slow stomach emptying, which lowers blood sugar and reduces appetite.
Source: Glucagon-Like Peptide-1 Receptor Agonists - StatPearls - NCBI Bookshelf
Other drug classes for diabetes mellitus, type 2
Get treated for diabetes mellitus, type 2 online
Licensed online providers — consult & get prescribed if eligible.
Advertising disclosure: We may earn a commission, at no extra cost to you. This never affects our ratings. Details
Top glp-1 receptor agonist for diabetes mellitus, type 2: 1. Ozempic · 2. Rybelsus · 3. Victoza
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | 70/100 | Prescription | Injectable | No data | — | View → | |
| 2 | 70/100 | Prescription | Tablet | No data | — | View → | |
| 3 | 70/100 | Prescription | Injectable | Generic | $39 | View → | |
| 4 | Not yet rated | Prescription | Injectable | No data | — | View → | |
| 5 | Not yet rated | Prescription | Injectable | No data | — | View → | |
| 6 | Not yet rated | Prescription | Injectable | No data | — | View → | |
| 7 | Not yet rated | Prescription | Injectable | No data | — | View → | |
| 8 | Not yet rated | Prescription | Injectable | No data | — | View → | |
| 9 | Not yet rated | Prescription | Injectable | No data | — | View → |
Full ranking · 9 drugs
ozempic
Boxed warningPrescriptionFDA-sourced
Ozempic (Semaglutide) is a GLP-1 receptor agonist used to treat Type 2 Diabetes Mellitus.
rybelsus
Boxed warningPrescriptionFDA-sourced
Rybelsus (Semaglutide) is a GLP-1 receptor agonist used to treat Type 2 Diabetes Mellitus.
victoza
Boxed warningPrescriptionFDA-sourced
Victoza (Liraglutide) is a GLP-1 receptor agonist used to treat Type 2 Diabetes Mellitus.
Pharmacy pays
From ~$35.39· 3 forms
mounjaro
Boxed warningPrescriptionFDA-sourced
Mounjaro (Tirzepatide) is a GLP-1 receptor agonist used to treat Type 2 Diabetes Mellitus.
mounjaro (autoinjector)
Boxed warningPrescriptionFDA-sourced
Mounjaro (Autoinjector) (Tirzepatide) is a GLP-1 receptor agonist used to treat Type 2 Diabetes Mellitus.
mounjaro kwikpen
Boxed warningPrescriptionFDA-sourced
Mounjaro Kwikpen (Tirzepatide) is a GLP-1 receptor agonist used to treat Type 2 Diabetes Mellitus.
zepbound
Boxed warningPrescriptionFDA-sourced
Zepbound (Tirzepatide) is a GLP-1 receptor agonist used to treat Type 2 Diabetes Mellitus.
zepbound (autoinjector)
Boxed warningPrescriptionFDA-sourced
Zepbound (Autoinjector) (Tirzepatide) is a GLP-1 receptor agonist used to treat Type 2 Diabetes Mellitus.
zepbound kwikpen
Boxed warningPrescriptionFDA-sourced
Zepbound Kwikpen (Tirzepatide) is a GLP-1 receptor agonist used to treat Type 2 Diabetes Mellitus.
Frequently asked
- What is the best glp-1 receptor agonist for diabetes mellitus, type 2?
- By our independent recall-safety rating — not an efficacy measure — ozempic ranks highest among GLP-1 Receptor Agonist drugs used for diabetes mellitus, type 2. Always consult a professional.
- Which glp-1 receptor agonist drugs treat diabetes mellitus, type 2?
- pharmaranks lists 9 GLP-1 Receptor Agonist products used for diabetes mellitus, type 2, per NIH RxClass drug-classification data — each independently rated and ranked above.
- How are these ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.