Skip to content
ppharmaranks
Menu
Novartis logo

zometa

Pharmaranks rates Zometa 3.5/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Zometa (Zoledronic Acid) is a bisphosphonate used to treat Bone Neoplasms, Hypercalcemia, Multiple Myeloma, Extramammary Paget Disease.

Zoledronic Acid · by Novartis

Available as a generic: Zoledronic Acid

70/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Zoledronic Acid
Drug class
Bisphosphonate
Form
Injectable
Strength
Zoledronic Acid EQ 4MG BASE/VIAL
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Novartis
What the pharmacy pays
~$0.47 per ml — not your price
FDA application
NDA021386

Drug class

How this class works, per Bisphosphonate - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

See how Zometa ranks — best-rated bisphosphonate for:

Dosage forms

Injectable

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Zometa treat?
Zometa (Zoledronic Acid) may be used to treat bone neoplasms, hypercalcemia, multiple myeloma, extramammary paget disease, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Zometa work?
Zometa is a bisphosphonate. Bisphosphonates stick to the mineral surface of bone, especially where it is being broken down. When the bone-dissolving cells (osteoclasts) take the drug up, it disables or kills them, slowing bone loss and helping keep bones denser and stronger.
How is Zometa rated?
pharmaranks gives Zometa a composite score of 3.5 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
How much does Zometa cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.47 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Zometa?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Zometa. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Zometa?
Zometa is marketed by Novartis. You can see Novartis's full profile, rating, and other products on pharmaranks.
Is Zometa a brand-name or generic drug?
Zometa is a brand-name product with the active ingredient Zoledronic Acid. Lower-cost generic equivalents containing Zoledronic Acid are available — ask your pharmacist.
Is Zometa available over the counter?
No. Zometa is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Zometa come in?
Zometa is currently marketed as injectable, per the FDA's National Drug Code Directory.
What class of drug is Zometa?
Zometa is classified as bisphosphonate, per the FDA's Established Pharmacologic Class.
Is Zometa FDA-registered?
Zometa is on record with the U.S. FDA under application number NDA021386. You can verify this on its official FDA label.
Has Zometa been recalled by the FDA?
Zometa has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Zometa safe?
There's no single safe-or-not verdict. pharmaranks gives Zometa a recall-safety score of 70/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

Reviews

No reviews yet. Be the first to write one.

Write a review

Reviews are user opinions, not medical advice. Consult a licensed professional.

People also viewed

Compare Zometa head-to-head

More bisphosphonate drugs

Guides for this medication

Identify a pill by its imprint →Check a drug interaction →Drug recalls →

Browse medications A–Z

Research products from A to Z, compare independent ratings, and find alternatives.