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aredia

Pharmaranks rates Aredia 3.5/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Aredia (Pamidronate Disodium) is a bisphosphonate used to treat Hypercalcemia, Osteolysis, Extramammary Paget Disease, Postmenopausal Osteoporosis.

Pamidronate Disodium · by Novartis

Available as a generic: Pamidronate Disodium

70/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated October 9, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Pamidronate Disodium
Drug class
Bisphosphonate
Form
Injectable
Strength
Pamidronate Disodium 30MG/VIAL · Pamidronate Disodium 60MG/VIAL · Pamidronate Disodium 90MG/VIAL
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Novartis
FDA application
NDA020927

Drug class

How this class works, per Bisphosphonate - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

See how Aredia ranks — best-rated bisphosphonate for:

Dosage forms

Injectable

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Aredia treat?
Aredia (Pamidronate Disodium) may be used to treat hypercalcemia, osteolysis, extramammary paget disease, postmenopausal osteoporosis, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Aredia work?
Aredia is a bisphosphonate. Bisphosphonates stick to the mineral surface of bone, especially where it is being broken down. When the bone-dissolving cells (osteoclasts) take the drug up, it disables or kills them, slowing bone loss and helping keep bones denser and stronger.
How is Aredia rated?
pharmaranks gives Aredia a composite score of 3.5 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
Is there a coupon or discount for Aredia?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Aredia. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Aredia?
Aredia is marketed by Novartis. You can see Novartis's full profile, rating, and other products on pharmaranks.
Is Aredia a brand-name or generic drug?
Aredia is a brand-name product with the active ingredient Pamidronate Disodium. Lower-cost generic equivalents containing Pamidronate Disodium are available — ask your pharmacist.
Is Aredia available over the counter?
No. Aredia is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Aredia come in?
Aredia is currently marketed as injectable, per the FDA's National Drug Code Directory.
What class of drug is Aredia?
Aredia is classified as bisphosphonate, per the FDA's Established Pharmacologic Class.
Is Aredia FDA-registered?
Aredia is on record with the U.S. FDA under application number NDA020927. You can verify this on its official FDA label.
Has Aredia been recalled by the FDA?
Aredia has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Aredia safe?
There's no single safe-or-not verdict. pharmaranks gives Aredia a recall-safety score of 70/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

What people report to the FDA about PAMIDRONATE DISODIUM

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 3,653 reports naming PAMIDRONATE DISODIUM — the active ingredient in Aredia, and the FDA flagged 94% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • osteonecrosis541 reports
  • osteonecrosis of jaw449 reports
  • nausea180 reports
  • bone disorder173 reports
  • fatigue171 reports
  • tooth extraction167 reports
  • diarrhoea162 reports
  • malignant neoplasm progression150 reports

Read these as a signal, not a rate. A report does not mean PAMIDRONATE DISODIUM caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 25, 2026.

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