Skip to content
ppharmaranks
Menu

Best Bisphosphonate for paget disease, extramammary

Top-rated pick: Aredia — pharmaranks score 70/100, the highest of the 8 Bisphosphonate drugs used for paget disease, extramammary, ranked by our independent FDA recall-safety score. Compare them with all treatments for paget disease, extramammary or the full Bisphosphonate class. Not medical advice — always consult a professional.

Quick answer: Of the 8 bisphosphonate drugs we rate for paget disease, extramammary, 7 are available as lower-cost generics, and most are injectable. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for paget disease, extramammary; the right choice depends on your situation, so confirm it with your prescriber.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

How bisphosphonate work

Bisphosphonates stick to the mineral surface of bone, especially where it is being broken down. When the bone-dissolving cells (osteoclasts) take the drug up, it disables or kills them, slowing bone loss and helping keep bones denser and stronger.

Source: Bisphosphonate - StatPearls - NCBI Bookshelf

Top bisphosphonate for paget disease, extramammary: 1. Aredia · 2. Zometa · 3. Reclast

Best-rated Bisphosphonate for paget disease, extramammary, ranked by pharmaranks score
#DrugRatingPharmacy pays
170/100View →
270/100$0View →
368/100$0View →
456/100$73View →
5Not yet rated$73View →
6Not yet rated$73View →
7Not yet rated$8View →
8Not yet rated$0View →

Full ranking · 8 drugs

NOVARTIS logo
#1 of 6 in Bisphosphonate

aredia

PrescriptionFDA-sourced

70/100

Aredia (Pamidronate Disodium) is a bisphosphonate used to treat Hypercalcemia, Osteolysis, Extramammary Paget Disease, Postmenopausal Osteoporosis.

(13 data points)
bisphosphonatehypercalcemiaosteolysis
Available online
View details →
NOVARTIS logo
#1 of 6 in Bisphosphonate

zometa

PrescriptionFDA-sourced

70/100

Zometa (Zoledronic Acid) is a bisphosphonate used to treat Bone Neoplasms, Hypercalcemia, Multiple Myeloma, Extramammary Paget Disease.

(13 data points)
bisphosphonatebone neoplasmshypercalcemia

Pharmacy pays

$0.47 /mL

View details →
SANDOZ logo

reclast

PrescriptionFDA-sourced

68/100

Reclast (Zoledronic Acid) is a bisphosphonate used to treat Bone Neoplasms, Hypercalcemia, Multiple Myeloma, Extramammary Paget Disease.

(23 data points)
bisphosphonatebone neoplasmshypercalcemia

Pharmacy pays

$0.47 /mL

View details →

risedronate sodium

PrescriptionFDA-sourced

56/100

Risedronate Sodium is a bisphosphonate used to treat Extramammary Paget Disease, Postmenopausal Osteoporosis.

(124 data points)
bisphosphonatepaget disease, extramammaryosteoporosis, postmenopausal

Pharmacy pays

From ~$44.10/30· 4 forms Save up to 89% in class
View details →

actonel

PrescriptionFDA-sourced

New

Actonel (Risedronate Sodium) is a bisphosphonate used to treat Extramammary Paget Disease, Postmenopausal Osteoporosis.

bisphosphonatepaget disease, extramammaryosteoporosis, postmenopausal

Pharmacy pays

From ~$44.10/30· 4 forms Save up to 89% in class
View details →

atelvia

PrescriptionFDA-sourced

New

Atelvia (Risedronate Sodium) is a bisphosphonate used to treat Extramammary Paget Disease, Postmenopausal Osteoporosis.

bisphosphonatepaget disease, extramammaryosteoporosis, postmenopausal

Pharmacy pays

From ~$44.10/30· 4 forms Save up to 89% in class
View details →

binosto

PrescriptionFDA-sourced

New

Binosto (Alendronate Sodium) is a bisphosphonate used to treat Extramammary Paget Disease, Postmenopausal Osteoporosis.

bisphosphonatepaget disease, extramammaryosteoporosis, postmenopausal

Pharmacy pays

From ~$3.63/30· 3 forms
View details →

zoledronic acid

PrescriptionFDA-sourced

New

Zoledronic Acid is a bisphosphonate used to treat Bone Neoplasms, Hypercalcemia, Multiple Myeloma, Extramammary Paget Disease.

bisphosphonatebone neoplasmshypercalcemia

Pharmacy pays

$0.47 /mL

View details →

Frequently asked

What is the best bisphosphonate for paget disease, extramammary?
By our independent recall-safety rating — not an efficacy measure — aredia ranks highest among Bisphosphonate drugs used for paget disease, extramammary. Always consult a professional.
Which bisphosphonate drugs treat paget disease, extramammary?
pharmaranks lists 8 Bisphosphonate products used for paget disease, extramammary, per NIH RxClass drug-classification data — each independently rated and ranked above.
How are these ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.